Some patients with glioblastoma may benefit from epidermal growth factor receptor inhibition
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34547
Abstract: 4175 What are the clinical implications? One key clinical implication of these findings is the suggestion that TNBC cells can develop resistance against therapies, says Dr Grasset, explaining that cancer cell heterogeneity and EMT are… read more here.
Keywords: may benefit; cancer; benefit epidermal; glioblastoma may ... See more keywords
Use of a neural network-based prediction method to calculate the therapeutic dose in boron neutron capture therapy of patients with glioblastoma.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16215
Abstract: BACKGROUND Boron neutron capture therapy (BNCT) is a binary radiotherapy based on the 10 B(n, α)7 Li capture reaction. Nonradioactive isotope 10 B atoms which selectively concentrated in tumor cells will react with low energy… read more here.
Keywords: therapeutic dose; patients glioblastoma; prediction method; method ... See more keywords
Radiomics in peritumoral non-enhancing regions: fractional anisotropy and cerebral blood volume improve prediction of local progression and overall survival in patients with glioblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Neuroradiology"
DOI: 10.1007/s00234-019-02255-4
Abstract: The peritumoral non-enhancing region (NER) is frequently not removed during the surgical resection of glioblastoma, with most recurrences occurring within the original treatment field. This study determined whether radiomics analysis of the NER can predict… read more here.
Keywords: patients glioblastoma; overall survival; local progression; survival patients ... See more keywords
Chemoradiation in elderly patients with glioblastoma from the multi-institutional GBM-molRPA cohort: is short-course radiotherapy enough or is it a matter of selection?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-020-03468-x
Abstract: Background The optimal radiotherapy regimen in elderly patients with glioblastoma treated by chemoradiation needs to be addressed. We provide the results of a comparison between conventionally fractionated standard radiotherapy (CRT) and short-course radiotherapy (SRT) in… read more here.
Keywords: patients glioblastoma; radiotherapy; short course; elderly patients ... See more keywords
Efficacy and safety of dendritic cell vaccines for patients with glioblastoma: A meta-analysis of randomized controlled trials.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106336
Abstract: BACKGROUND Dendritic cell (DC)-based vaccination has been suggested to be promising for glioblastoma. However, the evidence in randomized controlled trials (RCTs) is inconsistent. We aimed to systematically evaluate the efficacy and safety of DC vaccine… read more here.
Keywords: patients glioblastoma; randomized controlled; efficacy safety; vaccine ... See more keywords
Pattern of care and outcome in elderly patients with glioblastoma: Data in 151 patients from 3 Lombardia Hospitals
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2017.04.030
Abstract: The appropriate treatment approach for elderly patients with glioblastoma multiforme (GBM) is unclear, although different studies suggest survival benefit in fit patients treated with radiotherapy and chemiotherapy after surgery. We performed a retrospective analysis of… read more here.
Keywords: patients glioblastoma; 151 patients; lombardia hospitals; elderly patients ... See more keywords
Machine learning-based radiomic, clinical and semantic feature analysis for predicting overall survival and MGMT promoter methylation status in patients with glioblastoma.
Sign Up to like & getrecommendations! Published in 2020 at "Magnetic resonance imaging"
DOI: 10.1016/j.mri.2020.09.017
Abstract: INTRODUCTION Survival varies in patients with glioblastoma due to intratumoral heterogeneity and radiomics/imaging biomarkers have potential to demonstrate heterogeneity. The objective was to combine radiomic, semantic and clinical features to improve prediction of overall survival… read more here.
Keywords: status; patients glioblastoma; mgmt promoter; mgmt ... See more keywords
Perioperative Management of Patients with Glioblastoma.
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgery clinics of North America"
DOI: 10.1016/j.nec.2020.09.005
Abstract: The clinical presentation of glioblastomas is varied, and definitive diagnosis requires pathologic examination and study of the tissue. Management of glioblastomas includes surgery and adjuvant chemotherapy and radiotherapy, with surgery playing an important role in… read more here.
Keywords: management; perioperative management; patients glioblastoma; management patients ... See more keywords
Group Changes in Cognitive Performance After Surgery Mask Changes in Individual Patients with Glioblastoma.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.05.232
Abstract: BACKGROUND There is a growing interest to include evaluations of cognitive performance in the clinical management of patients with glioblastoma (GBM). However, as changes in cognitive performance of a group may mask changes in individual… read more here.
Keywords: patients glioblastoma; individual patients; cognitive performance; group ... See more keywords
Sarcopenia diagnosed using masseter muscle diameter as a survival correlate in elderly patients with glioblastoma.
Sign Up to like & getrecommendations! Published in 2022 at "World neurosurgery"
DOI: 10.1016/j.wneu.2022.02.038
Abstract: BACKGROUND Elderly patients with glioblastoma (GBM) have worse prognosis compared to younger patients. The study aimed to identify patient, treatment, and imaging features including measures of sarcopenia associated with worse survival and 90-day postoperative mortality… read more here.
Keywords: masseter; resection; elderly patients; muscle diameter ... See more keywords
Optimal managements of elderly patients with glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Japanese Journal of Clinical Oncology"
DOI: 10.1093/jjco/hyac075
Abstract: Abstract Optimizing the management of elderly patients with glioblastoma is an ongoing task in neuro-oncology. The number of patients with this tumor type is gradually increasing with the aging of the population. Although available data… read more here.
Keywords: oncology; elderly patients; managements elderly; patients glioblastoma ... See more keywords