Lacosamide in patients with gliomas and uncontrolled seizures: results from an observational study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2628-0
Abstract: To report the efficacy and tolerability of lacosamide as an add-on treatment in patients with gliomas and uncontrolled seizures despite conventional antiepileptic drugs (AEDs). We conducted an observational study on 71 patients to describe patterns… read more here.
Keywords: gliomas uncontrolled; observational study; study; seizure ... See more keywords
Diffusion kurtosis imaging combined with molecular markers as a comprehensive approach to predict overall survival in patients with gliomas.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2020.108985
Abstract: PURPOSE The purpose of this study was to explore the usefulness of diffusion kurtosis imaging (DKI) and molecular markers in predicting the prognosis of glioma patients. METHOD Fifty-one patients with gliomas were examined by conventional… read more here.
Keywords: molecular markers; kurtosis; kurtosis imaging; patients gliomas ... See more keywords
Clinical trial endpoints for patients with gliomas.
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology practice"
DOI: 10.1093/nop/npw034
Abstract: Malignant glioma represents a diverse set of molecularly heterogeneous diseases. Few therapeutic agents have been approved despite decades of clinical trials research and pre-clinical investigation. Attempts to refine neuroimaging criteria and recent discovery of the… read more here.
Keywords: clinical trial; trial; oncology; endpoints patients ... See more keywords
PRLHR Immune Genes Associated With Tumor Mutation Burden can be Used as Prognostic Markers in Patients With Gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.620190
Abstract: Tumor mutation burden (TMB) is a useful biomarker for predicting the prognosis and efficacy of immune checkpoint inhibitor (ICIs). In this study, we aimed to explore the prognostic value of TMB and TMB-related PRLHR immune… read more here.
Keywords: tumor mutation; patients gliomas; mutation burden; prlhr immune ... See more keywords
Detection of IDH1 Mutations in Plasma Using BEAMing Technology in Patients with Gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14122891
Abstract: Simple Summary In contrast with other solid tumors, only a few, small studies have shown the feasibility of detecting different biomarkers in the peripheral blood (PB) of patients with gliomas. A prospective study was conducted,… read more here.
Keywords: idh1; mutations plasma; patients gliomas; idh1 mutations ... See more keywords