International therapeutic guidelines for patients with HCV-related extrahepatic disorders. A multidisciplinary expert statement.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.03.004
Abstract: Hepatitis C virus (HCV) is both hepatotrophic and lymphotropic virus that causes liver as well extrahepatic manifestations including cryoglobulinemic vasculitis, the most frequent and studied condition, lymphoma, and neurologic, cardiovascular, endocrine-metabolic or renal diseases. HCV-extrahepatic… read more here.
Keywords: guidelines patients; therapeutic guidelines; hcv; hcv related ... See more keywords
Regulatory Analysis of Effects of Hepatitis C Virus NS5A Polymorphisms on Efficacy of Elbasvir and Grazoprevir.
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DOI: 10.1053/j.gastro.2016.10.017
Abstract: BACKGROUND & AIMS Elbasvir (an NS5A inhibitor) and grazoprevir (an NS3/4A protease inhibitor) are direct-acting antiviral agents recently approved in the United States for treatment of chronic hepatitis C virus (HCV) genotype 1 and 4… read more here.
Keywords: grazoprevir; elbasvir grazoprevir; treatment; hcv genotype ... See more keywords
Safety and Efficacy of Elbasvir/Grazoprevir in Patients With Hepatitis C Virus Infection and Compensated Cirrhosis: An Integrated Analysis.
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DOI: 10.1053/j.gastro.2017.01.050
Abstract: BACKGROUND & AIMS Persons with hepatitis C virus (HCV) infection are at risk of progressive liver disease, cirrhosis, and decompensation. We analyzed the effects of the direct-acting antiviral agents elbasvir and grazoprevir in patients with… read more here.
Keywords: elbasvir grazoprevir; treatment; infection; hcv genotype ... See more keywords
Assessment of the Prevalence of Non-Organ-Specific Autoantibodies in Egyptian Patients with HCV
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DOI: 10.1080/08820139.2019.1699108
Abstract: ABSTRACT The relation between non-organ specific autoantibodies (NOSA) and hepatitis C virus (HCV) infection has been investigated within different communities resulting in different prevalence rates and patterns. The purpose of this study was to investigate… read more here.
Keywords: organ specific; specific autoantibodies; non organ; egyptian patients ... See more keywords
Consensus statement on the management of patients with HCV infection in Romania.
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DOI: 10.18683/germs.2017.1106
Abstract: BACKGROUND HCV direct-acting antivirals (DAAs) have made treatment easier for both patients and healthcare practitioners, but have also brought new challenges in terms of patient management and monitoring prior to, during, and after treatment. METHODS… read more here.
Keywords: consensus statement; treatment; infection; hcv infection ... See more keywords
Clinical efficacy of free androgen index, a surrogate hallmark of circulating free testosterone level, in male patients with HCV-related chronic liver disease
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DOI: 10.3164/jcbn.18-30
Abstract: The role of free testosterone, that not bound to sex hormone-binding globulin, in male patients with HCV infection remains uncertain. We investigated whether free testosterone is involved in the progression to hepatic fibrosis/steatosis or insulin… read more here.
Keywords: free testosterone; testosterone; hepatic fibrosis; male patients ... See more keywords
Prognostic Factors for Overall Survival in Patients with HCV-Related HCC Undergoing Molecular Targeted Therapies: Beyond a Sustained Virological Response
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DOI: 10.3390/cancers14194850
Abstract: Simple Summary The eradication of the hepatitis C virus (HCV) has had a significant impact on the management of patients with HCV-related hepatocellular carcinoma (HCC). However, its eradication has not completely resolved survival issues in… read more here.
Keywords: prognostic factors; patients hcv; related hcc; hcc ... See more keywords
Direct-Acting Antiviral Agents for HCV-Associated Glomerular Disease and the Current Evidence
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DOI: 10.3390/pathogens8040176
Abstract: Glomerular disease is an extra-hepatic manifestation of hepatitis C virus infection (HCV) and membranoproliferative glomerulonephritis is the most frequent glomerular disease associated with HCV. It occurs commonly in patients with HCV-related mixed cryoglobulinemia syndrome. Patients… read more here.
Keywords: hcv associated; associated glomerular; disease; glomerular disease ... See more keywords
Silencing HCV Replication in Its Reservoir
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DOI: 10.3889/oamjms.2018.372
Abstract: BACKGROUND: HCV infection and its complications are among the leading public health challenges; the emergence of drug-resistant variants are expected to be a major problem. A novel combinatorial small interfering RNA (siRNA) could be a… read more here.
Keywords: reservoir; hcv; hcv replication; sirna ... See more keywords