Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphisms
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DOI: 10.1007/s00228-020-02831-1
Abstract: Aims Voriconazole (VCZ) displays highly variable pharmacokinetics affecting treatment efficacy and safety. We aimed to identify the factors affecting VCZ steady-state trough concentration (Cssmin) to provide evidence for optimizing VCZ treatment regimens. Methods A total… read more here.
Keywords: cssmin; hematopoietic stem; pxr; vcz ... See more keywords
Characterization of Oral Microbiota Following Chemotherapy in Patients With Hematopoietic Malignancies
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DOI: 10.1177/15347354231159309
Abstract: Oral microbiota may be associated with serious local or systemic medical conditions resulting from chemotherapy. This study was conducted to evaluate the changes in the oral microbiota following the initiation of chemotherapy in patients with… read more here.
Keywords: hematopoietic malignancies; chemotherapy patients; oral microbiota; patients hematopoietic ... See more keywords
The Effect of Continuous Screening of Carbapenem-Resistant Enterobacteriaceae on Theprevention and Control of Bloodstream Infections in Patients with Hematopoietic Stemcell Transplantation
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DOI: 10.1182/blood-2019-127599
Abstract: Carbapenem-resistant Enterobacteriaceae (CRE) bloodstream infections (BSIs) have become emerging cause of death in patients with hematopoietic stem cell transplantation (HSCT). Patients underwent HSCT from September 2017 to June 2018, and from July 2018 to February… read more here.
Keywords: resistant enterobacteriaceae; carbapenem resistant; continuous screening; bloodstream infections ... See more keywords