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Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3040
Abstract: Hepatocellular carcinoma (HCC) is a common malignant cancer and the third leading cause of death worldwide. The molecular mechanism of HCC remains unclear. Recent studies have demonstrated that the ubiquitin‐proteasome system (UPS) is associated with… read more here.
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Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30185
Abstract: Prognostic assessment of patients with hepatocellular carcinoma (HCC) at the time of diagnosis remains controversial and becomes even more complex at the time of restaging when new variables need to be considered. The aim of… read more here.
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Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13053
Abstract: Access to the liver transplant waitlist for patients with hepatocellular carcinoma (HCC) depends on tumour presentation, biology, and response to treatments. The Milan Criteria (MC) represent the benchmark for expanded criteria that incorporate additional prognostic… read more here.
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Published in 2018 at "Liver Transplantation"
DOI: 10.1002/lt.24977
Abstract: A subset of patients with hepatocellular carcinoma (HCC) beyond Milan criteria might obtain acceptable survival outcomes after liver transplantation. Living donor liver transplantation (LDLT) has emerged as a feasible alternative to overcome the paucity of… read more here.
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Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03727-y
Abstract: The dynamics of serum alpha-fetoprotein (AFP) level have been found to be a useful predictor of therapeutic responsiveness in patients with hepatocellular carcinoma (HCC). We evaluated whether AFP changes were able to accurately reflect imaging-based… read more here.
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Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06384-2
Abstract: Background/Aim The prognosis of patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE) is highly heterogeneous because of variable characteristics of tumor burden and liver dysfunction. We aimed to propose and validate an albumin–bilirubin (ALBI)… read more here.
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Published in 2018 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-018-3981-9
Abstract: BackgroundWe aimed to explore the benefit of splenectomy combined with curative treatments (liver resection or local ablation) for patients with hepatocellular carcinoma and portal hypertension.MethodsThe records of 239 patients with hepatocellular carcinoma and portal hypertension… read more here.
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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-04633-7
Abstract: Patients with hepatocellular carcinoma (HCC) always require routine surveillance and repeated treatment, which leads to accumulation of huge amount of clinical data. A predictive model utilizes the time-series data to facilitate dynamic prognosis prediction and… read more here.
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09696-y
Abstract: Clinical outcomes of patients with hepatocellular carcinoma (HCC) are highly variable. This study aims to identify and validate a simple, readily available, and objective prognostic index for the management of HCC. Data from 724 HCC… read more here.
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Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20192690
Abstract: Abstract Background and aim: Assessing the average survival rate of patients with hepatocellular carcinoma (HCC) after hepatectomy is important for making critical decisions in everyday clinical practice. The present study aims to develop and validate… read more here.