Sex-Based Outcomes in Patients With a High Bleeding Risk After Percutaneous Coronary Intervention and 1-Month Dual Antiplatelet Therapy: A Secondary Analysis of the LEADERS FREE Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.0285
Abstract: Importance Female sex has been identified as a risk factor for bleeding after percutaneous coronary intervention (PCI) and may have contributed to the underuse of drug-eluting stents in women. This risk may be further enhanced… read more here.
Keywords: risk; high bleeding; trial; sex ... See more keywords
Effect of C-Reactive Protein on Lipoprotein(a)-Associated Cardiovascular Risk in Optimally Treated Patients With High-Risk Vascular Disease: A Prespecified Secondary Analysis of the ACCELERATE Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.2413
Abstract: Importance Although lipoprotein(a) (Lp[a]) is a causal genetic risk factor for atherosclerotic cardiovascular disease, it remains unclear which patients with established atherosclerotic cardiovascular disease stand to benefit the most from Lp(a) lowering. Whether inflammation can… read more here.
Keywords: protein; risk; analysis; high risk ... See more keywords
Assessment of Outcomes From 1-Year Surveillance After Detection of Early Gastric Cancer Among Patients at High Risk in Japan
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.27667
Abstract: Key Points Question Is new gastric cancer (GC) detectable approximately 1 year after intensive index endoscopic examination using both white light and narrow-band imaging among patients with a high risk of GC? Findings In this… read more here.
Keywords: year; patients high; high risk; gastric cancer ... See more keywords
Comparison of Sequential Intravesical Gemcitabine and Docetaxel vs Bacillus Calmette-Guérin for the Treatment of Patients With High-Risk Non–Muscle-Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.0849
Abstract: Key Points Question Is there a difference in outcomes associated with sequential intravesical gemcitabine and docetaxel therapy vs bacillus Calmette-Guérin (BCG) therapy, the standard of care for the treatment of high-risk non–muscle-invasive bladder cancer (NMIBC)?… read more here.
Keywords: gemcitabine docetaxel; high risk; patients high;
Effect of Oral β-Glucan on Antibody Response to Ganglioside Vaccine in Patients With High-Risk Neuroblastoma: A Phase 2 Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2022.5999
Abstract: Importance Among patients with high-risk relapsed metastatic neuroblastoma, oral β-glucan adjuvant during GD2/GD3 ganglioside vaccine boost has stimulated IgG antibody response, which was associated with improved survival; however, the effectiveness of oral β-glucan during the… read more here.
Keywords: patients high; high risk; oral glucan; vaccine ... See more keywords
Pancreaticojejunostomy With Externalized Stent vs Pancreaticogastrostomy With Externalized Stent for Patients With High-Risk Pancreatic Anastomosis: A Single-Center, Phase 3, Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA surgery"
DOI: 10.1001/jamasurg.2019.6035
Abstract: Importance The operative scenarios with the highest postoperative pancreatic fistula (POPF) risk represent situations in which fistula prevention and mitigation strategies have the strongest potential to affect surgical outcomes after pancreaticoduodenectomy. Evidence from studies providing… read more here.
Keywords: risk; high risk; fistula; risk pancreatic ... See more keywords
Evaluation of the Merit-Based Incentive Payment System and Surgeons Caring for Patients at High Social Risk.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA surgery"
DOI: 10.1001/jamasurg.2021.3746
Abstract: Importance The latest step in the Centers for Medicaid & Medicare transformation to pay-for-value is the Medicare Merit-Based Incentive Payment System (MIPS). Value-based payment designs often do not account for uncaptured clinical status and social… read more here.
Keywords: risk; high social; payment; social risk ... See more keywords
TSLP induces a proinflammatory phenotype in circulating innate cells and predicts prognosis in sepsis patients
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12746
Abstract: Thymic stromal lymphopoietin (TSLP) has been identified as a crucial inflammatory cytokine in immune homeostasis. Previous studies have reported conflicting effects of TSLP on sepsis in mice, and the effect of TSLP on sepsis in… read more here.
Keywords: sepsis; tslp induces; levels tslp; phenotype circulating ... See more keywords
Meta‐analysis of mortality in patients with high‐risk intraductal papillary mucinous neoplasms under observation
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DOI: 10.1002/bjs.10768
Abstract: Although consensus guidelines suggest that patients with high‐risk intraductal papillary mucinous neoplasms (IPMNs) should have surgery, a non‐operative strategy is often selected in patients who are poor surgical candidates. The aim was to determine the… read more here.
Keywords: risk; papillary mucinous; high risk; risk intraductal ... See more keywords
Germline large deletion of BAP1 and decreased expression in non‐tumor choroid in uveal melanoma patients with high risk for inherited cancer
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1002/gcc.22752
Abstract: Uveal melanoma (UM) is the most common phenotype in patients with germline BAP1 mutation. This study aimed to identify selection criteria for BAP1 germline testing and assessed the role of large deletion/duplication and epigenetic inactivation.… read more here.
Keywords: bap1; large deletion; uveal melanoma; deletion ... See more keywords
Clinical outcomes and prognostic factors for patients with high‐risk gastrointestinal stromal tumors treated with 3‐year adjuvant imatinib
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34157
Abstract: Three years of adjuvant imatinib is the current standard for patients with high‐risk gastrointestinal stromal tumors (GIST). We aimed to investigate the safety and efficacy profiles of 3‐year imatinib, focusing on the prognostic value of… read more here.
Keywords: year; adjuvant imatinib; patients high; high risk ... See more keywords