Altered expression of caveolin-1 in the colon of patients with Hirschsprung’s disease
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DOI: 10.1007/s00383-019-04505-1
Abstract: The pathogenesis of Hirschsprung’s disease-associated enterocolitis (HAEC) is unclear. Caveolin-1 (Cav-1) regulates the functions of different nitric oxide synthase (NOS) isoforms, which play critical roles in inflammation and intestinal epithelial barrier function. We designed this… read more here.
Keywords: microscopy; patients hirschsprung; hirschsprung disease; expression ... See more keywords
The overall risk of malignancies is not increased in patients with Hirschsprung disease
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DOI: 10.1007/s00383-020-04631-1
Abstract: Purpose Hirschsprung disease (HSCR) has previously been associated with increased risk of medullary thyroid cancer. The aim of this study was to assess the overall risk of malignancies in patients with Hirschsprung disease in a… read more here.
Keywords: risk; risk malignancies; patients hirschsprung; hirschsprung disease ... See more keywords
Risk factors for enterocolitis in patients with Hirschsprung disease: A retrospective observational study.
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DOI: 10.1016/j.jpedsurg.2021.04.020
Abstract: INTRODUCTION Hirschsprung-associated enterocolitis (HAEC) accounts for substantial morbidity and mortality in patients with Hirschsprung disease (HD). The aim of this study was to identify incidence of pre- and postoperative HAEC in our consecutive cohort and… read more here.
Keywords: postoperative haec; risk; haec; patients hirschsprung ... See more keywords