Association of HLA class I homozygosity with unfavorable clinical outcomes in patients with non-small cell lung cancer treated with chemo-immunotherapy or immunotherapy as first-line therapy
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DOI: 10.1016/j.heliyon.2021.e07916
Abstract: Background Homozygosity at HLA-I locus has been reported to be an unfavorable predictive biomarker of second-line or beyond immunotherapy in patients with different types of cancer. The linkage between HLA-I zygosity and survival in NSCLC… read more here.
Keywords: immunotherapy; line; first line; patients hla ... See more keywords
HLA Allele Distribution Associated with Adverse Drug Reactions in Organ Transplant Patients
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DOI: 10.3233/shti190680
Abstract: The results of Human Leukocyte Antigen (HLA) antigen testing in transplant patients are not generally used to predict future adverse events. In this study, free-text HLA screening results of transplant patients were analyzed and stored… read more here.
Keywords: hla allele; patients hla; allele distribution; drug ... See more keywords