A specific diagnostic metabolome signature in adult IgA vasculitis
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DOI: 10.1007/s11306-024-02107-0
Abstract: IgA vasculitis diagnosis relies primarily on clinical features and is confirmed by pathological findings. To date, there is no reliable noninvasive diagnostic biomarker. We aimed to explore the baseline serum metabolome of adult patients with… read more here.
Keywords: vasculitis; adult iga; iga vasculitis; patients iga ... See more keywords
P0301FIT FOR PURPOSE VALIDATION OF A CLINICAL ASSAY FOR THE DETECTION OF SERUM LEVELS OF GALACTOSE-DEFICIENT IMMUNOGLOBULIN A1 (GD-IGA1) IN PATIENTS WITH IGA NEPHROPATHY (IGAN)
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p0301
Abstract: Analysis of serum or plasma from patients with IgA nephropathy (IgAN) has confirmed the presence of elevated levels of circulating immune complexes containing Gd-IgA1 (Czerkinsky 1986). New sensitive and reasonably specific noninvasive tests are emerging… read more here.
Keywords: nephropathy igan; iga nephropathy; validation; patients iga ... See more keywords
P0432GAMMA DELTA T-CELLS PHENOTYPIC PROFILE IN PATIENTS WITH IGA-NEPHROPATHY
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DOI: 10.1093/ndt/gfaa142.p0432
Abstract: γδТ-lymphocytes are enigmatic minor nonconventional peripheral blood cells population responded to non-peptidic antigens and displayed functional diversity, from effector action to immunoregulation, depending on pathological conditions. Although γδТ-lymphocytes are known to play a key role… read more here.
Keywords: iga nephropathy; cd45ro cd27; patients iga; igan patients ... See more keywords
#2809 Peroxiredoxins, the potential predictor of eGFR decline in patients with IgA nephropathy
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DOI: 10.1093/ndt/gfae069.1229
Abstract: Multiple factors may contribute to development and progression of glomerulopathies (GN), one of them is oxidative stress (OS). 2-cysteine-peroxiredoxins (PRDXs) possess the ability to reduce excessive levels of OS mediators and are crucial for cellular… read more here.
Keywords: 2809 peroxiredoxins; peroxiredoxins potential; patients iga; iga nephropathy ... See more keywords
The gut microbiota posttranslationally modifies IgA1 in autoimmune glomerulonephritis
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DOI: 10.1126/scitranslmed.adl6149
Abstract: Mechanisms underlying the disruption of self-tolerance in acquired autoimmunity remain unclear. Immunoglobulin A (IgA) nephropathy is an acquired autoimmune disease where deglycosylated IgA1 (IgA subclass 1) auto-antigens are recognized by IgG auto-antibodies, forming immune complexes… read more here.
Keywords: patients iga; gut microbiota; muciniphila; iga nephropathy ... See more keywords
Prediction models for the survival in patients with intestinal-type gastric adenocarcinoma: a retrospective cohort study based on the SEER database
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DOI: 10.1136/bmjopen-2022-070803
Abstract: Objective To explore the influencing factors of survival in intestinal-type gastric adenocarcinoma (IGA) and set up prediction model for the prediction of survival of patients diagnosed with IGA. Design A retrospective cohort study. Setting and… read more here.
Keywords: patients iga; prediction models; prediction; stage ... See more keywords