Comparison of administration of single- and triple-course steroid pulse therapy combined with tonsillectomy for immunoglobulin A nephropathy
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DOI: 10.1097/md.0000000000027778
Abstract: Abstract Immunoglobulin A nephropathy (IgAN) is a form of chronic glomerulonephritis that can cause end-stage renal disease. Recently, tonsillectomy combined with corticosteroid pulse (TSP) has been shown to be effective for achieving clinical remission and… read more here.
Keywords: course; patients igan; triple course; corticosteroid pulse ... See more keywords
Mechanism of Yiqi Yangying Heluo Formula in the Treatment of IgA Nephropathy by Affecting Gd-IgA1 Based on BAFF Molecular Level and T Lymphocyte Immunity
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DOI: 10.1155/2023/5124034
Abstract: Background Galactose-deficient IgA1 (Gd-IgA1) is a critical initiating factor in the pathogenesis of IgA nephropathy (IgAN), which plays an important role in the diagnosis and evaluation of this disease. Moreover, the whole pathogenesis process has… read more here.
Keywords: patients igan; treg; level; peripheral blood ... See more keywords
TLR7 in B cells promotes renal inflammation and Gd-IgA1 synthesis in IgA nephropathy.
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DOI: 10.1172/jci.insight.136965
Abstract: TLR7 has been linked to the pathogenesis of glomerulonephritis, but its precise roles are not clear. In this study, we evaluated the roles of TLR7 in IgA nephropathy (IgAN). TLR7 proteins were abundant in CD19+… read more here.
Keywords: tlr7; iga nephropathy; inflammation iga1; renal inflammation ... See more keywords
Gut Microbiome Characteristics in IgA Nephropathy: Qualitative and Quantitative Analysis from Observational Studies
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DOI: 10.3389/fcimb.2022.904401
Abstract: Background Recent data indicate the importance of gut-kidney axis in the pathogenesis of Immunoglobulin A nephropathy (IgAN). Growing evidence suggests the alterations of diversity and composition of gut microbiome among patients with IgAN, however, the… read more here.
Keywords: patients igan; microbiome characteristics; diversity; analysis ... See more keywords
High Neutrophil-To-Lymphocyte Ratio Is an Independent Risk Factor for End Stage Renal Diseases in IgA Nephropathy
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DOI: 10.3389/fimmu.2021.700224
Abstract: Background Complex factors are involved in the development and progression of immunoglobulin A nephropathy (IgAN), a common primary glomerulonephritis worldwide. Autoimmunity and inflammation have been considered to be the basic mechanisms; however, the exact pathogenesis… read more here.
Keywords: stage renal; neutrophil lymphocyte; lymphocyte ratio; independent risk ... See more keywords
Gut Dysbiosis and Intestinal Barrier Dysfunction Promotes IgA Nephropathy by Increasing the Production of Gd-IgA1
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DOI: 10.3389/fmed.2022.944027
Abstract: Background Immunoglobulin A nephropathy (IgAN) is the most common type of primary glomerular disease in adults worldwide. Several studies have reported that galactose-deficient IgA1 (Gd-IgA1) is involved in the pathogenesis of IgAN. Methods Thirty-five patients… read more here.
Keywords: patients igan; intestinal barrier; dysbiosis intestinal; iga1 ... See more keywords