Steroid therapy still plays a crucial role and could serve as a bridge to the next promising treatments in patients with IgG4-related sclerosing cholangitis: Results of a Japanese Nationwide Study.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of hepato-biliary-pancreatic sciences"
DOI: 10.1002/jhbp.1157
Abstract: OBJECTIVE The acceptable duration of steroid therapy for patients with IgG4-sclerosing cholangitis (SC) has been under debate. Our aim is to clarify the feasible duration of steroid treatment. DESIGN We retrospectively reviewed the data of… read more here.
Keywords: steroid therapy; therapy; patients igg4; sclerosing cholangitis ... See more keywords
Treatment of chronic inflammatory demyelinating polyradiculoneuropathy patients with antibodies against paranodal proteins
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DOI: 10.1111/cen3.12590
Abstract: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired immune‐mediated polyneuropathy characterized by relapsing or steadily progressive clinical course. A major feature of the syndrome is that it encompasses several pathogeneses, and it is actually assumed… read more here.
Keywords: inflammatory demyelinating; patients igg4; demyelinating polyradiculoneuropathy; treatment ... See more keywords
Reducing relapse through maintenance steroid treatment can decrease the cancer risk in patients with IgG4‐sclerosing cholangitis: Based on a Japanese nationwide study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.16066
Abstract: IgG4‐related sclerosing cholangitis (IgG4‐SC) is recognized as a benign steroid‐responsive disease; however, little is known about the risk of development of cancer in patients with IgG4‐SC and about how to counter this risk. read more here.
Keywords: sclerosing cholangitis; reducing relapse; risk; patients igg4 ... See more keywords
IgG4-related disease administered dupilumab: case series and review of the literature
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DOI: 10.1136/rmdopen-2023-003026
Abstract: Dupilumab (DUP) is a monoclonal antibody that acts on the interleukin (IL)-4 receptor alpha, which inhibits IL-4 and IL-13 signalling and is approved for type 2 inflammatory diseases such as asthma, chronic rhinosinusitis with nasal… read more here.
Keywords: igg4 related; disease; related disease; case ... See more keywords
Clinical Characteristics of Patients With IgG4-Related Disease Complicated by Hypocomplementemia
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DOI: 10.3389/fimmu.2022.828122
Abstract: Background A proportion of patients with immunogloblin G (IgG) 4-related disease (IgG4-RD) have hypocomplementemia. We aimed to identify characteristics of such patients. Methods We analyzed the demographic and clinical data and complement levels of 85… read more here.
Keywords: igg4; related disease; patients hypocomplementemia; patients igg4 ... See more keywords
Role of apoptosis inhibitor of macrophages in patients with IgG4‑related disease/autoimmune pancreatitis and the clinical characteristics associated with this condition
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DOI: 10.3892/br.2022.1565
Abstract: Type 1 autoimmune pancreatitis (AIP) is a pancreatic manifestation of IgG4-related disease (IgG4-RD) and is a unique chronic inflammatory disease characterized by fibrosis. IgG4-RD is caused by an autoimmune mechanism that mimics malignant tumors and… read more here.
Keywords: igg4 related; serum aim; autoimmune pancreatitis; disease ... See more keywords
Frequency and distribution of CD4+CXCR5+ follicular B helper T cells within involved tissues in IgG4-related ophthalmic disease
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DOI: 10.3892/mmr.2017.7780
Abstract: Immonoglobulin G4-related ophthalmic disease (IgG4-ROD) is a IgG4-RD and exhibits two main characteristics: Fibrosis that is not necessarily marked histopathologically; and frequent formation of germinal centers (GCs). Follicular B helper T (Tfh) cells are now… read more here.
Keywords: patients igg4; tfh; igg4 rod; tfh cells ... See more keywords