Investigation of clinical predictors of survival in idiopathic pulmonary fibrosis patients: A cohort study in Taiwan
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DOI: 10.1097/jcma.0000000000000719
Abstract: Background: Two antifibrotic medications, pirfenidone and nintedanib, have been approved as treatments for idiopathic pulmonary fibrosis (IPF)—a life-threatening interstitial lung disease. However, there are insufficient current data regarding clinical predictors of survival for patients with… read more here.
Keywords: patients ipf; clinical predictors; idiopathic pulmonary; pulmonary fibrosis ... See more keywords
CC-90001, a c-Jun N-terminal kinase (JNK) inhibitor, in patients with pulmonary fibrosis: design of a phase 2, randomised, placebo-controlled trial
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DOI: 10.1136/bmjresp-2021-001060
Abstract: Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive and often fatal interstitial lung disease (ILD); other ILDs have a progressive, fibrotic phenotype (PF-ILD). Antifibrotic agents can slow but not stop disease progression in patients with… read more here.
Keywords: week; placebo; jun terminal; pulmonary fibrosis ... See more keywords
Patterns of discontinuation in patients with IPF treated with open-label nintedanib: data from INPULSIS-ON
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DOI: 10.1183/13993003.congress-2018.pa4777
Abstract: INPULSIS®-ON Ulrich Costabel,1 Michael Kreuter,2 Jin Woo Song,3 John T Huggins,4 Benoit Wallaert,5 Wibke Stansen,6 Susanne Stowasser,6 Manuel Quaresma,6 Bruno Crestani7 1Ruhrlandklinik, University Hospital, University of Duisburg-Essen, Essen, Germany; 2Center for Interstitial and Rare Lung… read more here.
Keywords: ipf treated; patterns discontinuation; patients ipf; university ... See more keywords
The St. George’s Respiratory Questionnaire as a prognostic factor in IPF
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DOI: 10.1186/s12931-017-0503-3
Abstract: BackgroundIt is unclear whether health related quality of life (HRQL) may have a predictive value for mortality in idiopathic pulmonary fibrosis (IPF).We investigated the relationship between HRQL assessed using the St. George’s Respiratory Questionnaire (SGRQ)… read more here.
Keywords: respiratory questionnaire; george respiratory; patients ipf; mortality ... See more keywords
Evaluation for clinical benefit of metformin in patients with idiopathic pulmonary fibrosis and type 2 diabetes mellitus: a national claims-based cohort analysis
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DOI: 10.1186/s12931-022-02001-0
Abstract: Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with high morbidity and limited treatment options. Type 2 diabetes mellitus (T2DM) is a common comorbid illness among patients with IPF and is often… read more here.
Keywords: patients ipf; pulmonary fibrosis; cohort; type diabetes ... See more keywords
Clinical impact of depression and anxiety in patients with idiopathic pulmonary fibrosis
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DOI: 10.1371/journal.pone.0184300
Abstract: Background Although depression and anxiety represent significant yet treatable comorbidities in patients with idiopathic pulmonary fibrosis (IPF), their impact on the clinical course and prognosis of IPF remain unclear. Purpose We investigated the prevalence and… read more here.
Keywords: idiopathic pulmonary; anxiety; patients ipf; depression anxiety ... See more keywords
S100A12 as Biomarker of Disease Severity and Prognosis in Patients With Idiopathic Pulmonary Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.810338
Abstract: Background Idiopathic pulmonary fibrosis (IPF) is one of interstitial lung diseases (ILDs) with poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a prognostic serum biomarker in the IPF, but its correlation… read more here.
Keywords: patients ipf; biomarker; idiopathic pulmonary; s100a12 ... See more keywords
Serum Concentrations of KL-6 in Patients with IPF and Lung Cancer and Serial Measurements of KL-6 in IPF Patients Treated with Antifibrotic Therapy
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DOI: 10.3390/cancers13040689
Abstract: Simple Summary Evaluation of the prognostic significance of serial measurements of serum concentrations of Krebs von den Lungen-6 (KL-6) showed that an annual increment in KL-6 exceeding a threshold amount was an independent risk factor… read more here.
Keywords: patients ipf; ipf lung; serum concentrations; ipf patients ... See more keywords