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   Articles with "patients itp" as a keyword



Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia.

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recommendations! Published in 2022 at "Platelets"

DOI: 10.1080/09537104.2022.2144194

Abstract: The association between T-cell large granular lymphocytes (T-LGL) and ITP is uncertain. The aims of this study were to determine the prevalence of T-LGL in patients with ITP and to describe its association with ITP… read more here.

Keywords: patients itp; itp patients; itp; lgl ... See more keywords

The costs of treating bleeding episodes in patients with immune thrombocytopaenia in the United Kingdom.

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recommendations! Published in 2025 at "Hematology"

DOI: 10.1080/16078454.2025.2458359

Abstract: ABSTRACT Objectives Immune thrombocytopaenia (ITP) is a rare autoimmune disorder characterized by low platelet count and increased risk of bleeding. This study aimed to be the first publication to characterize the economic burden of bleeding… read more here.

Keywords: immune thrombocytopaenia; bleeding events; life threatening; event ... See more keywords

Itaconate derivative 4-OI inhibits M1 macrophage polarization and restores its impaired function in immune thrombocytopenia through metabolic reprogramming

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recommendations! Published in 2025 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000003586

Abstract: Abstract Background: Macrophage polarization anomalies and dysfunction play a crucial role in the pathogenesis of immune thrombocytopenia (ITP). Itaconate is a Krebs cycle-derived immunometabolite synthesized by myeloid cells to modulate cellular metabolism and inflammatory responses.… read more here.

Keywords: itaconate derivative; macrophage polarization; immune thrombocytopenia; macrophage ... See more keywords
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Is it the therapy or the disease? Exploring the link between treatment for immune thrombocytopenia and thrombosis

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recommendations! Published in 2021 at "British Journal of Haematology"

DOI: 10.1111/bjh.17745

Abstract: Patients with immune thrombocytopenia (ITP) have low platelet counts, which may increase bleeding risk, but they are not protected from thrombosis. Multiple studies suggest that the risk of thrombosis is higher in patients with ITP… read more here.

Keywords: risk; treatment; thrombotic risk; thrombosis ... See more keywords

Association of metformin treatment and outcome in adult patients with ITP and pre‐existing T2DM

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recommendations! Published in 2022 at "British Journal of Haematology"

DOI: 10.1111/bjh.18121

Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune haemorrhagic disease that could manifest with comorbid type 2 diabetes mellitus (T2DM). However, the exact impact of T2DM in patients with ITP remains uncertain. In this study, we… read more here.

Keywords: existing t2dm; patients itp; pre existing; association metformin ... See more keywords

Real-World Use of Fostamatinib in Patients with Immune Thrombocytopenia and Thrombotic Risk

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recommendations! Published in 2021 at "Acta Haematologica"

DOI: 10.1159/000520438

Abstract: Patients with immune thrombocytopenia (ITP) are at increased risk for bleeding and are paradoxically at increased risk for thrombosis. Many patients with ITP have underlying cardiovascular (CV) disease and/or other thrombotic risk factors for which… read more here.

Keywords: risk; thrombotic risk; patients itp; real world ... See more keywords

Decreased Frequency of IL-17F rs763780 Site Allele G is Associated With Genetic Susceptibility to Immune Thrombocytopenia in a Chinese Population

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recommendations! Published in 2017 at "Clinical and Applied Thrombosis/Hemostasis"

DOI: 10.1177/1076029615618022

Abstract: Interleukin 17F (IL-17F) is an inflammatory cytokine that plays an important role in autoimmune disease by inducing the expression of multiple chemokines, cytokines, and adhesion molecules. In vitro functional analysis revealed that IL-17F rs763780 polymorphism… read more here.

Keywords: 17f rs763780; rs763780; immune thrombocytopenia; population ... See more keywords

Comparing BAT and Beighton Scores in Patients with ITP: A Retrospective Observational Cohort Study

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recommendations! Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-211567

Abstract: Introduction Immune thrombocytopenic purpura (ITP) is an acquired thrombocytopenia that leads to clinically significant bleeding in many. The Bleeding Assessment Tool (BAT) is a validated tool used to assess the degree of bleeding with scoring… read more here.

Keywords: beighton scores; beighton; bat beighton; hypermobility ... See more keywords

Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0207149

Abstract: Mucosal-associated invariant T (MAIT) cells help protect against certain infections and are related to some autoimmune diseases. Immune thrombocytopenia (ITP) is a relatively rare hematological autoimmune disease associated with low platelet count. We designed a… read more here.

Keywords: response; mait cells; mait; number ... See more keywords