Prevalence and significance of large granular lymphocytes in patients with immune thrombocytopenia.
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DOI: 10.1080/09537104.2022.2144194
Abstract: The association between T-cell large granular lymphocytes (T-LGL) and ITP is uncertain. The aims of this study were to determine the prevalence of T-LGL in patients with ITP and to describe its association with ITP… read more here.
Keywords: patients itp; itp patients; itp; lgl ... See more keywords
Is it the therapy or the disease? Exploring the link between treatment for immune thrombocytopenia and thrombosis
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DOI: 10.1111/bjh.17745
Abstract: Patients with immune thrombocytopenia (ITP) have low platelet counts, which may increase bleeding risk, but they are not protected from thrombosis. Multiple studies suggest that the risk of thrombosis is higher in patients with ITP… read more here.
Keywords: risk; treatment; thrombotic risk; thrombosis ... See more keywords
Association of metformin treatment and outcome in adult patients with ITP and pre‐existing T2DM
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DOI: 10.1111/bjh.18121
Abstract: Primary immune thrombocytopenia (ITP) is an autoimmune haemorrhagic disease that could manifest with comorbid type 2 diabetes mellitus (T2DM). However, the exact impact of T2DM in patients with ITP remains uncertain. In this study, we… read more here.
Keywords: existing t2dm; patients itp; pre existing; association metformin ... See more keywords
Real-World Use of Fostamatinib in Patients with Immune Thrombocytopenia and Thrombotic Risk
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DOI: 10.1159/000520438
Abstract: Patients with immune thrombocytopenia (ITP) are at increased risk for bleeding and are paradoxically at increased risk for thrombosis. Many patients with ITP have underlying cardiovascular (CV) disease and/or other thrombotic risk factors for which… read more here.
Keywords: risk; thrombotic risk; patients itp; real world ... See more keywords
Decreased Frequency of IL-17F rs763780 Site Allele G is Associated With Genetic Susceptibility to Immune Thrombocytopenia in a Chinese Population
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DOI: 10.1177/1076029615618022
Abstract: Interleukin 17F (IL-17F) is an inflammatory cytokine that plays an important role in autoimmune disease by inducing the expression of multiple chemokines, cytokines, and adhesion molecules. In vitro functional analysis revealed that IL-17F rs763780 polymorphism… read more here.
Keywords: 17f rs763780; rs763780; immune thrombocytopenia; population ... See more keywords
Low mucosal-associated invariant T-cell number in peripheral blood of patients with immune thrombocytopenia and their response to prednisolone
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DOI: 10.1371/journal.pone.0207149
Abstract: Mucosal-associated invariant T (MAIT) cells help protect against certain infections and are related to some autoimmune diseases. Immune thrombocytopenia (ITP) is a relatively rare hematological autoimmune disease associated with low platelet count. We designed a… read more here.
Keywords: response; mait cells; mait; number ... See more keywords