LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "patients major" as a keyword



Effectiveness of Genotype-Specific Tricyclic Antidepressant Dosing in Patients With Major Depressive Disorder

Sign Up to like & get
recommendations! Published in 2023 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2023.12443

Abstract: Key Points Question Does pharmacogenetics-informed (CYP2D6 and CYP2C19 genotypes) dosing of tricyclic antidepressants result in faster attainment of therapeutic plasma concentrations, higher effectiveness, and fewer and less severe adverse effects compared with usual treatment? Findings… read more here.

Keywords: effectiveness genotype; depressive disorder; patients major; major depressive ... See more keywords

Association of Brain Cortical Changes With Relapse in Patients With Major Depressive Disorder

Sign Up to like & get
recommendations! Published in 2018 at "JAMA Psychiatry"

DOI: 10.1001/jamapsychiatry.2018.0123

Abstract: Importance More than half of all patients with major depressive disorder (MDD) experience a relapse within 2 years after recovery. It is unclear how relapse affects brain morphologic features during the course of MDD. Objective… read more here.

Keywords: difference; volume; age; relapse ... See more keywords

Efficacy and Safety of Ketamine vs Electroconvulsive Therapy Among Patients With Major Depressive Episode: A Systematic Review and Meta-analysis.

Sign Up to like & get
recommendations! Published in 2022 at "JAMA psychiatry"

DOI: 10.1001/jamapsychiatry.2022.3352

Abstract: Importance Whether ketamine is as effective as electroconvulsive therapy (ECT) among patients with major depressive episode remains unknown. Objective To systematically review and meta-analyze data about clinical efficacy and safety for ketamine and ECT in… read more here.

Keywords: review meta; ketamine; depressive episode; patients major ... See more keywords

Patients Having Major Abdominal Cancer Surgery Exhibit Significant Acute Muscle Wasting

Sign Up to like & get
recommendations! Published in 2025 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.13858

Abstract: Postoperative myopenia (acute muscle loss) is a significant concern following major cancer resection surgery, contributing to prolonged recovery, increased dependency and impaired quality of life. Despite its clinical relevance, the mechanisms underlying postoperative myopenia and… read more here.

Keywords: surgery; cancer; muscle; patients major ... See more keywords

A web‐based survey on the occurrence of emotional blunting in patients with major depressive disorder in Japan: Patient perceptions and attitudes

Sign Up to like & get
recommendations! Published in 2024 at "Neuropsychopharmacology Reports"

DOI: 10.1002/npr2.12417

Abstract: To determine the prevalence and impact of emotional blunting (EB) in patients with major depressive disorder (MDD) in Japan, and identify treatment needs for EB using patients' perceptions and attitudes. read more here.

Keywords: blunting patients; depressive disorder; patients major; major depressive ... See more keywords

Altered B Cell Homeostasis in Patients with Major Depressive Disorder and Normalization of CD5 Surface Expression on Regulatory B Cells in Treatment Responders

Sign Up to like & get
recommendations! Published in 2017 at "Journal of Neuroimmune Pharmacology"

DOI: 10.1007/s11481-017-9763-4

Abstract: Pro-inflammatory activity and cell-mediated immune responses have been widely observed in patients with major depressive disorder (MDD). Besides their well-known function as antibody-producers, B cells play a key role in inflammatory responses by secreting pro-… read more here.

Keywords: cd5 surface; cell; surface expression; patients major ... See more keywords

Earlier Versus Later Augmentation with an Antipsychotic Medication in Patients with Major Depressive Disorder Demonstrating Inadequate Efficacy in Response to Antidepressants: A Retrospective Analysis of US Claims Data

Sign Up to like & get
recommendations! Published in 2018 at "Advances in Therapy"

DOI: 10.1007/s12325-018-0838-2

Abstract: IntroductionThere is little evidence regarding the most effective timing of augmentation of antidepressants (AD) with antipsychotics (AP) in patients with major depressive disorder (MDD) who inadequately respond to first-line AD (inadequate responders). The study’s objective… read more here.

Keywords: depressive disorder; disorder; major depressive; augmentation ... See more keywords
Photo from wikipedia

Gambling in patients with major depressive disorder is associated with an elevated risk of Suicide: Insights from 12-years of Nationwide inpatient sample data.

Sign Up to like & get
recommendations! Published in 2021 at "Addictive behaviors"

DOI: 10.1016/j.addbeh.2021.106872

Abstract: BACKGROUND There is a frequent occurrence of gambling disorder (GD) in patients with major depressive disorder (MDD). Psychiatric comorbidities can present more severely in patients diagnosed with pathological gambling. There is limited information on symptom… read more here.

Keywords: mdd patients; risk; diagnosis; disorder ... See more keywords

Efficacy and tolerability of pharmacological and non-pharmacological interventions in older patients with major depressive disorder: A systematic review, pairwise and network meta-analysis

Sign Up to like & get
recommendations! Published in 2019 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2019.07.130

Abstract: As there is currently no comprehensive evaluation about the efficacy and safety of interventions in elderly patients with major depressive disorder, we did a systematic review and network meta-analysis about all interventions in this population.… read more here.

Keywords: network meta; depressive disorder; patients major; major depressive ... See more keywords
Photo from wikipedia

Add-on benzodiazepine treatment in patients with major depressive disorder – results from a European cross-sectional multicenter study

Sign Up to like & get
recommendations! Published in 2020 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2020.09.636

Abstract: Since many patients with major depressive disorder (MDD) do not satisfactorily respond to initial antidepressant monotherapy, add-on treatment strategies with other psychiatric compounds are often established. The present European multicenter cross-sectional study comprising 1410 MDD… read more here.

Keywords: depressive disorder; treatment; disorder; study ... See more keywords

Alterations in patients with major depressive disorder before and after electroconvulsive therapy measured by fractional amplitude of low-frequency fluctuations (fALFF).

Sign Up to like & get
recommendations! Published in 2019 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2018.10.099

Abstract: BACKGROUND Electroconvulsive therapy (ECT) is an important treatment option for patients with major depressive disorder (MDD). However, the mechanisms of ECT in MDD are still unclear. METHODS Twenty-four patients with severe MDD and 14 healthy… read more here.

Keywords: depressive disorder; ect; major depressive; gyrus ... See more keywords