Real-World Treatment Costs and Care Utilization in Patients with Major Depressive Disorder With and Without Psychiatric Comorbidities in Specialist Mental Healthcare
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacoeconomics"
DOI: 10.1007/s40273-021-01012-x
Abstract: Background The majority of patients with major depressive disorder (MDD) have comorbid mental conditions. Objectives Since most cost-of-illness studies correct for comorbidity, this study focuses on mental healthcare utilization and treatment costs in patients with… read more here.
Keywords: mental healthcare; psychiatric comorbidities; patients mdd; treatment ... See more keywords
Elevated triglyceride levels are associated with cognitive impairments among patients with major depressive disorder.
Sign Up to like & getrecommendations! Published in 2017 at "Comprehensive psychiatry"
DOI: 10.1016/j.comppsych.2017.03.007
Abstract: BACKGROUND Cognitive deficits have been identified as one of core clinical symptoms of major depressive disorder (MDD). Accumulating evidence indicated that triglycerides (TG) might be associated with MDD and cognitive decline. OBJECTIVE This study examined… read more here.
Keywords: depressive disorder; patients mdd; cognitive impairments; healthy controls ... See more keywords
Dissociative symptoms are associated with neurocognitive dysfunction in patients with MDD
Sign Up to like & getrecommendations! Published in 2017 at "European Psychiatry"
DOI: 10.1016/j.eurpsy.2017.02.334
Abstract: Introduction It is widely reported that persons with major depressive disorder (MDD) show impaired performance on cognitive functioning, including frontotemporally mediated cognitive functions. The presence of cognitive dysfunction among patients with dissociative symptoms in trauma-related… read more here.
Keywords: patients mdd; dysfunction patients; performance; dissociative symptoms ... See more keywords
Shared and distinct changes in local dynamic functional connectivity patterns in major depressive and bipolar depressive disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2021.10.109
Abstract: BACKGROUND Distinguishing bipolar depressive disorder (BDD) from major depressive disorder (MDD) solely relying on clinical clues is a challenge. Evidence in neuroimaging have revealed potential neurological markers for the differential diagnosis. METHODS We aimed to… read more here.
Keywords: disorders shared; patients mdd; connectivity; major depressive ... See more keywords
Ketamine normalizes subgenual cingulate cortex hyper-activity in depression
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DOI: 10.1038/s41386-019-0591-5
Abstract: Mounting evidence supports the rapid antidepressant efficacy of the N -methyl- d -aspartate receptor antagonist, ketamine, for treating major depressive disorder (MDD); however, its neural mechanism of action remains poorly understood. Subgenual anterior cingulate cortex… read more here.
Keywords: patients mdd; sgacc hyper; ketamine; hyper activity ... See more keywords
Genetic and molecular basis of abnormal BOLD signaling variability in patients with major depressive disorder after electroconvulsive therapy
Sign Up to like & getrecommendations! Published in 2025 at "Translational Psychiatry"
DOI: 10.1038/s41398-025-03330-6
Abstract: Electroconvulsive therapy (ECT) is an effective and rapid neuromodulatory intervention for treatment-resistant major depressive disorders (MDD). However, the precise mechanisms underlying their efficacies remain unclear. Resting-state functional magnetic resonance imaging (fMRI) data were collected from… read more here.
Keywords: electroconvulsive therapy; major depressive; patients mdd; genetic molecular ... See more keywords
Association between cognitive deficits and suicidal ideation in patients with major depressive disorder
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DOI: 10.1038/s41598-017-12142-8
Abstract: The role of cognitive function in suicidal ideation in patients with major depressive disorder (MDD) has not been adequately explored. This research sought to measure the relationship between suicidal ideation and cognitive function. Therefore, in… read more here.
Keywords: patients mdd; suicidal ideation; cognitive function; function ... See more keywords
1098 Altered Actigraphic Behavioral Activity Rhythm In Depression
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DOI: 10.1093/sleep/zsaa056.1093
Abstract: Disturbances in sleep and behavioral activity rhythms (BAR) are frequently observed in individuals with depression. However, it remains unclear how activity variability across the 24-hour period is specifically associated with this disorder. The present study… read more here.
Keywords: depression; behavioral activity; patients mdd; hour ... See more keywords
Economic burden and antidepressant treatment patterns among patients with major depressive disorder in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of managed care & specialty pharmacy"
DOI: 10.18553/jmcp.2022.28.11-a.s1
Abstract: BACKGROUND: The prevalence of major depressive disorder (MDD) continues to rise year over year, resulting in significant economic implications. However, when patients are treated with contemporary standard-of-care antidepressant pharmacotherapies, a suboptimal response is often attained,… read more here.
Keywords: non mdd; patients mdd; treatment patterns; among patients ... See more keywords
Relationship between social determinants of health and hospitalizations and costs in patients with major depressive disorder.
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DOI: 10.18553/jmcp.2024.30.9.978
Abstract: BACKGROUND The relationship of patient characteristics and social determinants of health (SDOH) with hospitalizations and costs in patients with major depressive disorder (MDD) has not been assessed using real-world data. OBJECTIVE To identify factors associated… read more here.
Keywords: hospitalizations costs; commercial medicaid; patients mdd; associated higher ... See more keywords
Quality of life in euthymic patients with unipolar major depressive disorder and bipolar disorder
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s201567
Abstract: Objective: This study aimed to compare quality of life (QOL) between patients with major depressive disorder (MDD) in remission and patients with bipolar disorder (BD) in remission, and to explore the relationship between QOL and… read more here.
Keywords: quality life; euthymic patients; patients mdd; scale ... See more keywords