Iron overload in patients with myelodysplastic syndromes: An updated overview
Sign Up to like & getrecommendations! Published in 2018 at "Cancer"
DOI: 10.1002/cncr.31550
Abstract: Myelodysplastic syndromes (MDS) encompass a heterogeneous group of clonal hematopoietic stem cell disorders characterized by a broad clinical spectrum related to ineffective hematopoiesis leading to unilineage or multilineage cytopenias, with a high propensity for transformation… read more here.
Keywords: overload patients; myelodysplastic syndromes; patients mds; iron overload ... See more keywords
Circulating HMGB1 is increased in myelodysplastic syndrome but not in other bone marrow failure syndromes: proof-of-concept cross-sectional study
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Hematology"
DOI: 10.1177/20406207221125990
Abstract: Background: Myelodysplastic syndrome (MDS) is associated with persistent immune activation. High mobility group box-1 (HMGB1) is a ubiquitous, functionally diverse, non-histone intranuclear protein. During acute and chronic inflammatory states, HMGB1 is actively released by inflammatory… read more here.
Keywords: myelodysplastic syndrome; circulating hmgb1; iqr; hmgb1 ... See more keywords
WT1 mRNA Expression in the Peripheral Blood of Patients with MDS Yields Additional Prognostic Information within the IPSS-R Risk Categories "Very Low", "Low" and "Intermediate"
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DOI: 10.1182/blood-2018-99-113524
Abstract: Introduction: The revised version of the International Prognostic Scoring System, (IPSS-R), is an accepted standard for assessing the prognosis of patients with MDS. Its usefulness may be further improved by integrating molecular findings. However, such… read more here.
Keywords: risk; patients mds; ipss; expression ... See more keywords
Real-World Application of Molecular Genetic Sequencing in the Management of Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes: The Wisconsin Experience
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DOI: 10.1182/blood-2019-123676
Abstract: Background: Next-generation sequencing (NGS) technologies have led to the discovery of recurrently-mutated genes in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). These mutations have proven useful in diagnosis, prognostication, and prediction of treatment response… read more here.
Keywords: risk; aml patients; molecular data; patients mds ... See more keywords
Sleep Disturbance Among Patients with Myelodysplastic Syndromes and Acute Leukemia
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DOI: 10.1182/blood-2019-125147
Abstract: BACKGROUND: Most patients with myelodysplastic syndromes (MDS) describe difficulty sleeping (Luskin et al Br J Haem 2017) and sleep disturbance is a likely contributor to the fatigue experienced by patients with MDS and acute leukemia.… read more here.
Keywords: acute leukemia; patients mds; consultancy; research funding ... See more keywords
First Cytogenetic Profile of Omani Patients with de novo Myelodysplastic Syndromes: Comparison with data from Asia, Africa, Europe and North and South America.
Sign Up to like & getrecommendations! Published in 2017 at "Sultan Qaboos University medical journal"
DOI: 10.18295/squmj.2017.17.03.005
Abstract: Clonal cytogenetic abnormalities have been reported among 30-80% of patients with myelodysplastic syndromes (MDS); however, 20-70% of patients with MDS show a normal karyotype that may nevertheless harbour a cryptic genetic alteration. Earlier reports have… read more here.
Keywords: profile omani; myelodysplastic syndromes; patients mds; omani patients ... See more keywords
Myelodysplastic Syndromes with Bone Marrow Fibrosis: An Update
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DOI: 10.3343/alm.2022.42.3.299
Abstract: Myelodysplastic syndrome (MDS) is a diverse hematological malignancy with a wide spectrum of presentations and implications. Treatment strategies for patients with MDS heavily rely on prognostic scoring systems, such as the revised international prognostic scoring… read more here.
Keywords: syndromes bone; bone marrow; myelodysplastic syndromes; patients mds ... See more keywords