Development and Validation of a Nomogram for Assessing Survival in Patients With Metastatic Lung Cancer Referred for Radiotherapy for Bone Metastases
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.3242
Abstract: Key Points Question What are the optimal factors to use for constructing a nomogram to assess the probability of survival in patients with bone metastases arising from lung cancer? Findings This prognostic study of 477… read more here.
Keywords: bone metastases; patients metastatic; survival patients; lung cancer ... See more keywords
Cost-effectiveness Analysis of Genetic Testing and Tailored First-Line Therapy for Patients With Metastatic Gastrointestinal Stromal Tumors
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.13565
Abstract: Key Points Question Is targeted gene testing cost-effective in patients with metastatic gastrointestinal stromal tumor? Findings This economic evaluation developed a Markov model to examine the cost-effectiveness of targeted gene testing with tailored imatinib dosing… read more here.
Keywords: metastatic gastrointestinal; patients metastatic; gastrointestinal stromal; testing tailored ... See more keywords
Survival Outcomes Associated With Cytoreductive Nephrectomy in Patients With Metastatic Clear Cell Renal Cell Carcinoma
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DOI: 10.1001/jamanetworkopen.2022.12347
Abstract: Key Points Question Is cytoreductive nephrectomy associated with improved overall survival for patients with metastatic clear cell renal cell carcinoma? Findings In this cohort study of 12 766 patients, receipt of a cytoreductive nephrectomy was not… read more here.
Keywords: cell; survival; cytoreductive nephrectomy; metastatic clear ... See more keywords
Association of Allostatic Load With Overall Mortality Among Patients With Metastatic Non–Small Cell Lung Cancer
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DOI: 10.1001/jamanetworkopen.2022.21626
Abstract: Key Points Question Is there an association among allostatic load (AL), social determinants of health (SDHs), and overall mortality in patients with metastatic non–small cell lung cancer (NSCLC)? Findings In this cross-sectional study of 143… read more here.
Keywords: non small; metastatic non; patients metastatic; overall mortality ... See more keywords
Use of First-Line Immune Checkpoint Inhibitors and Association With Overall Survival Among Patients With Metastatic Melanoma in the Anti–PD-1 Era
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DOI: 10.1001/jamanetworkopen.2022.25459
Abstract: Key Points Question Following the US Food and Drug Administration’s approval of PD-1 immune checkpoint inhibitors (ICI) for metastatic melanoma, what were the utilization and overall survival associated with ICI in the first-line setting after… read more here.
Keywords: first line; overall survival; line; metastatic melanoma ... See more keywords
Comparative Effectiveness of Immune Checkpoint Inhibitors vs Chemotherapy in Patients With Metastatic Colorectal Cancer With Measures of Microsatellite Instability, Mismatch Repair, or Tumor Mutational Burden
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DOI: 10.1001/jamanetworkopen.2022.52244
Abstract: This comparative effectiveness research study compares outcomes of first-line therapy with immune checkpoint inhibitors vs chemotherapy among patients who have metastatic colorectal cancer with high microsatellite instability, mismatch repair deficiency, and/or high tumor mutational burden. read more here.
Keywords: checkpoint inhibitors; immune checkpoint; metastatic colorectal; inhibitors chemotherapy ... See more keywords
Association of Antibiotic Receipt With Survival Among Patients With Metastatic Pancreatic Ductal Adenocarcinoma Receiving Chemotherapy
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DOI: 10.1001/jamanetworkopen.2023.4254
Abstract: Key Points Question Is antibiotic therapy associated with response to chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma (PDAC)? Findings In this cohort study of 3850 older adults with metastatic PDAC, receipt of perichemotherapy antibiotics… read more here.
Keywords: metastatic pancreatic; ductal adenocarcinoma; survival among; pancreatic ductal ... See more keywords
Immune Checkpoint Inhibitors and Long-term Survival of Patients With Metastatic Urothelial Cancer
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DOI: 10.1001/jamanetworkopen.2023.7444
Abstract: This cohort study uses published clinical trial data to assess long-term survival of patients with metastatic urothelial carcinoma who are treated with immune checkpoint inhibitors. read more here.
Keywords: long term; immune checkpoint; metastatic urothelial; term survival ... See more keywords
Atezolizumab Plus Bevacizumab as First-line Treatment for Patients With Metastatic Nonsquamous Non–Small Cell Lung Cancer With High Tumor Mutation Burden
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2022.5959
Abstract: This nonrandomized controlled trial evaluates the clinical benefits and safety of atezolizumab plus bevacizumab for treatment of patients with metastatic non–small cell lung cancer (NSCLC) with high tumor mutation burden. read more here.
Keywords: non small; treatment patients; small cell; atezolizumab plus ... See more keywords
Phase 1 trial of ADI‐PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors
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DOI: 10.1002/cam4.4446
Abstract: Arginine depletion interferes with pyrimidine metabolism and DNA damage repair pathways. Preclinical data demonstrated that depletion of arginine by PEGylated arginine deiminase (ADI‐PEG 20) enhanced liposomal doxorubicin (PLD) cytotoxicity in cancer cells with argininosuccinate synthase… read more here.
Keywords: liposomal doxorubicin; solid tumors; adi peg; metastatic solid ... See more keywords
Multidimensional financial hardship among uninsured and insured young adult patients with metastatic breast cancer.
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DOI: 10.1002/cam4.5885
Abstract: Little is known about the heterogeneous nature of financial hardship in younger patients with metastatic disease and the extent to which insurance protects against it. We examine the association between insurance status and multidimensional indicators… read more here.
Keywords: financial hardship; breast cancer; metastatic breast; patients metastatic ... See more keywords