Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis
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DOI: 10.1001/jamadermatol.2022.0029
Abstract: This analysis of 2 randomized clinical trials evaluates long-term (52 weeks) efficacy and safety of upadacitinib treatment in patients with atopic dermatitis. read more here.
Keywords: safety upadacitinib; upadacitinib patients; efficacy safety; atopic dermatitis ... See more keywords
Bimekizumab Safety in Patients With Moderate to Severe Plaque Psoriasis
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DOI: 10.1001/jamadermatol.2022.1185
Abstract: Key Points Question What is the 2-year safety profile of bimekizumab in patients with moderate to severe plaque psoriasis? Findings In this cohort study including 1789 patients receiving bimekizumab, pooled data on 2 years of… read more here.
Keywords: safety; patients moderate; moderate severe; plaque psoriasis ... See more keywords
Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19
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DOI: 10.1001/jamanetworkopen.2022.3890
Abstract: This cohort study investigates whether early aspirin use is associated with lower 28-day in-hospital mortality among patients with moderate COVID-19. read more here.
Keywords: aspirin use; hospital mortality; moderate covid; early aspirin ... See more keywords
Clinical significance of IgE in a large cohort of patients with moderate or severe chronic graft‐versus‐host disease
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24768
Abstract: in arterial and venous thromboelastography parameters: potential roles of shear stress and oxygen content. J Cardiothorac Vasc Anesth. 2002;16(5):551–554. [5] White H, Zollinger C, Jones M, Bird R. Can thromboelastography performed on kaolin-activated citrated samples… read more here.
Keywords: significance ige; large cohort; cohort patients; patients moderate ... See more keywords
Patients with moderate chronic kidney disease without heart disease have reduced coronary flow velocity reserve
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12878
Abstract: The overall aim was to identify sub‐clinical cardiac abnormalities by echocardiography in patients with chronic kidney disease (CKD) stages 3 and 4 and to investigate underlying mechanisms. read more here.
Keywords: heart; chronic kidney; disease; patients moderate ... See more keywords
Prognostic relevance of B‐type natriuretic peptide in patients with moderate mixed aortic valve disease
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DOI: 10.1002/ehf2.13946
Abstract: Data on B‐type natriuretic peptide (BNP) levels and adverse outcomes in patients with moderate mixed aortic valve disease (MAVD), defined as moderate aortic stenosis (AS) and regurgitation (AR), are scarce. Therefore, this study investigated the… read more here.
Keywords: aortic valve; natriuretic peptide; type natriuretic; mixed aortic ... See more keywords
Relationship Between Anifrolumab Pharmacokinetics, Pharmacodynamics, and Efficacy in Patients With Moderate to Severe Systemic Lupus Erythematosus
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DOI: 10.1002/jcph.2054
Abstract: This study aimed to elucidate the pharmacokinetic/pharmacodynamic and pharmacodynamic/efficacy relationships of anifrolumab, a type I interferon receptor antibody, in patients with moderate to severe systemic lupus erythematosus. Data were pooled from the randomized, 52‐week, placebo‐controlled… read more here.
Keywords: neutralization; efficacy; systemic lupus; lupus erythematosus ... See more keywords
Efficacy of bracing in skeletally immature patients with moderate-severe idiopathic scoliosis curves between 40° and 60°.
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DOI: 10.1007/s43390-020-00131-3
Abstract: STUDY DESIGN Retrospective case-series. OBJECTIVES To evaluate the outcomes of bracing in skeletally immature patients with moderate-severe idiopathic scoliosis (IS) curves ≥ 40°. BACKGROUND In contrast to prior beliefs, the recent studies have reported successful outcomes with… read more here.
Keywords: skeletally immature; patients moderate; bracing skeletally; immature patients ... See more keywords
Efficacy of hypericum extract Ws® 5570 compared with paroxetine in patients with a moderate major depressive episode–a subgroup analysis
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DOI: 10.1016/j.eurpsy.2017.01.716
Abstract: Introduction Various studies showed the efficacy and tolerability of WS® 5570 (Hyperiplant® Rx, Dr. Willmar Schwabe GmbH & Co. KG) for the treatment of acute mild-to moderate depression. Beneficial effects of WS® 5570 have been… read more here.
Keywords: depression; subgroup; analysis; 5570 compared ... See more keywords
Low-dose subcutaneous tocilizumab to prevent disease progression in patients with moderate COVID-19 pneumonia and hyperinflammation
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DOI: 10.1016/j.ijid.2020.07.078
Abstract: Abstract Aim The aim of the study was to evaluate the safety and efficacy profile of low-dose tocilizumab (TCZ) administered subcutaneously to patients with moderate COVID-19 pneumonia and hyperinflammation to prevent disease progression. Methods We… read more here.
Keywords: hyperinflammation; low dose; moderate covid; patients moderate ... See more keywords
A pilot study for treatment of COVID-19 patients in moderate stage using intravenous administration of ozonized saline as an adjuvant treatment-registered clinical trial
Sign Up to like & getrecommendations! Published in 2021 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2021.107743
Abstract: Objective Ozone therapy has tremendous therapeutic potential owing to its antiviral, anti-inflammatory and antioxidant properties, and potential to improve oxygenation. A pilot clinical trial was conducted to evaluate the safety and efficacy ofintravenous ozonised saline… read more here.
Keywords: clinical trial; treatment; study; patients moderate ... See more keywords