Survival analysis of elderly patients with osteosarcoma
Sign Up to like & getrecommendations! Published in 2019 at "International Orthopaedics"
DOI: 10.1007/s00264-019-04332-y
Abstract: BackgroundFew studies have described the characteristics and prognostic factors of elderly patients with osteosarcoma. We retrospectively investigated clinico-pathological features and prognostic factors in osteosarcoma patients > 40 years old.MethodsPatients with high-grade osteosarcoma > 40 years old who were treated… read more here.
Keywords: chemotherapy; years old; analysis; patients osteosarcoma ... See more keywords
Relationship between red cell distribution width and prognosis of patients with osteosarcoma
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20192590
Abstract: Abstract We retrospectively collected the clinical data and follow-up information of patients with osteosarcoma who were admitted to Department of Orthopedics, RenMin Hospital of Wuhan University from January 2010 to December 2016 and explore the… read more here.
Keywords: rdw group; rdw; patients osteosarcoma; prognosis ... See more keywords
Association of hypoxia-inducible factor 1 expressions with prognosis role as a survival prognostic biomarker in the patients with osteosarcoma: a meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2157719
Abstract: ABSTRACT Background Osteosarcoma, the most prevalent primary bone cancer, tends to relapse or metastasize quickly. Hypoxia-inducible factor-1 alpha (HIF-1α) affects tumor metabolism, differentiation, angiogenesis, proliferation, and metastasis. Many studies have investigated the possible inconsistent prognostic… read more here.
Keywords: meta analysis; inducible factor; patients osteosarcoma; hypoxia inducible ... See more keywords
A Phase 1 and pharmacokinetic study evaluating daily or weekly schedules of the humanized anti-GD2 antibody hu14.18K322A in recurrent/refractory solid tumors
Sign Up to like & getrecommendations! Published in 2020 at "mAbs"
DOI: 10.1080/19420862.2020.1773751
Abstract: ABSTRACT Hu14.18K322A is a humanized anti-GD2 monoclonal antibody with a single point mutation that reduces complement-mediated cytotoxicity, with a maximum tolerated dose (MTD) of 60 mg/m2 daily for 4 days in children with recurrent/refractory neuroblastoma.… read more here.
Keywords: humanized anti; anti gd2; schedule; patients osteosarcoma ... See more keywords
Are Pathologic Fractures in Patients With Osteosarcoma Associated With Worse Survival Outcomes? A Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical orthopaedics and related research"
DOI: 10.1097/corr.0000000000002687
Abstract: BACKGROUND Pathologic fractures occur in 5% to 10% of patients with osteosarcoma, and prior studies have suggested they are prognostically important. However, because they represent an uncommon event in the setting of an already rare… read more here.
Keywords: patients osteosarcoma; pathologic fractures; survival; local recurrence ... See more keywords
Toxicity of high-dose chemotherapy in patients with osteosarcoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e14508
Abstract: e14508Background: We monitored the level of methotrexate and some laboratory parameters in patients with osteosarcoma to evaluate the toxicity of high-dosage EURAMOS chemotherapy. Methods: The stud... read more here.
Keywords: dose chemotherapy; high dose; chemotherapy patients; patients osteosarcoma ... See more keywords
Risk Factors for Hepatic Toxicity of High-dose Methotrexate in Patients With Osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.15565
Abstract: Background/Aim: High-dose methotrexate (HD-MTX) is widely used to treat osteosarcoma. However, some patients develop hepatic toxicity, leading to dose modification and delays in the scheduled chemotherapy. The present study aimed to identify the risk factors… read more here.
Keywords: patients osteosarcoma; dose methotrexate; risk factors; hepatotoxicity ... See more keywords
Pretreatment Neutrophil Count and Platelet-lymphocyte Ratio as Predictors of Metastasis in Patients With Osteosarcoma
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.15570
Abstract: Background/Aim: Systemic inflammation responses have been associated with cancer development, progression and metastasis. Little is known about the risk of metastasis based on inflammatory-based scores in patients with osteosarcoma. Patients and Methods: A total of… read more here.
Keywords: metastasis; patients osteosarcoma; lymphocyte ratio; platelet lymphocyte ... See more keywords
Risk of Cardiovascular Death in Osteosarcoma.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the College of Physicians and Surgeons--Pakistan : JCPSP"
DOI: 10.29271/jcpsp.2023.03.266
Abstract: OBJECTIVE To assess the risk of cardiovascular mortality (CVM) in patients with osteosarcoma. STUDY DESIGN Descriptive study. Place and Duration of the Study: Department of Orthopaedics, The People's Hospital of Baoan, Shenzhen, Guangdong, China, from 1st… read more here.
Keywords: risk cardiovascular; patients osteosarcoma; death osteosarcoma; risk ... See more keywords
A validation study for the utility of serum microRNA as a diagnostic and prognostic marker in patients with osteosarcoma
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Letters"
DOI: 10.3892/ol.2023.13808
Abstract: In our previous study, osteosarcoma advanced locally, and metastasis was promoted through the secretion of large number of small extracellular vesicles, followed by suppressing osteoclastogenesis via the upregulation of microRNA (miR)-146a-5p. An additional 12 miRNAs… read more here.
Keywords: patients osteosarcoma; serum; survival rate; utility ... See more keywords
Predicting chemosensitivity based on mini patient-derived xenografts in osteosarcoma patients: A retrospective study
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_825_22
Abstract: Context: The survival of patients diagnosed with osteosarcoma has not improved in the past three decades because of chemoresistance. Aim: This study aimed to improve the prognosis of patients with osteosarcoma. Settings and Design: From… read more here.
Keywords: patients osteosarcoma; mini patient; patient derived; based mini ... See more keywords