Articles with "patients pah" as a keyword



Real-World Switching to Riociguat: Management and Practicalities in Patients with PAH and CTEPH

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Published in 2018 at "Lung"

DOI: 10.1007/s00408-018-0100-3

Abstract: PurposeA proportion of patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) do not achieve treatment goals or experience side effects on their current therapy. In such cases, switching patients to a… read more here.

Keywords: real world; clinical practice; patients pah; world ... See more keywords

Macitentan and Tadalafil Combination Therapy in Patients with Pulmonary Arterial Hypertension and Cardiovascular Comorbidities: Real-World Evidence from OPUS and OrPHeUS

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Published in 2025 at "Advances in Therapy"

DOI: 10.1007/s12325-025-03180-0

Abstract: Patients diagnosed with pulmonary arterial hypertension (PAH) often present with risk factors associated with cardiovascular disease, including diabetes mellitus (DM), hypertension (HTN), and obesity. The 2022 ESC/ERS pulmonary hypertension treatment guidelines recommend initial monotherapy with… read more here.

Keywords: combination therapy; combination; cardiovascular comorbidities; patients pah ... See more keywords

Effects of beta blockers on outcome in patients with PAH with and without comorbid conditions: a Multicenter Prospective Cohort Study (BNP-PL)

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Published in 2024 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehae666.2179

Abstract: The current guidelines do not recommend the use of beta-blockers (BB) in patients with pulmonary arterial hypertension (PAH) unless necessitated by comorbidities. However, the evidence regarding the role of BB in PAH is contradictory. This… read more here.

Keywords: composite endpoint; cause mortality; mortality; patients pah ... See more keywords
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Pulmonary arterial hypertension: promising advances and remaining challenges

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Published in 2021 at "Journal of Investigative Medicine"

DOI: 10.1136/jim-2021-002152

Abstract: © American Federation for Medical Research 2021. No commercial reuse. See rights and permissions. Published by BMJ. Pulmonary arterial hypertension (PAH) diagnosis and management have evolved over the years. Despite advances in management that resulted… read more here.

Keywords: medicine; earlier diagnosis; patients pah; disease ... See more keywords

Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension

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Published in 2022 at "Circulation"

DOI: 10.1161/circulationaha.121.056719

Abstract: Background: Cell-free DNA (cfDNA) is a noninvasive marker of cellular injury. Its significance in pulmonary arterial hypertension (PAH) is unknown. Methods: Plasma cfDNA was measured in 2 PAH cohorts (A, n=48; B, n=161) and controls… read more here.

Keywords: reveal; patients pah; cell free; cfdna ... See more keywords

Epidemiology and initial management of pulmonary arterial hypertension: real-world data from the Hellenic pulmOnary hyPertension rEgistry (HOPE)

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Published in 2019 at "Pulmonary Circulation"

DOI: 10.1177/2045894019877157

Abstract: Pulmonary arterial hypertension (PAH) is a heterogenous clinical entity with poor prognosis, despite recent major pharmacological advances. To increase awareness about the pathophysiology, epidemiology, and management of the disease, large national registries are required. The… read more here.

Keywords: pulmonary hypertension; arterial hypertension; patients pah; pulmonary arterial ... See more keywords

Atrial septostomy in the management of pulmonary arterial hypertension: past, present, and future

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Published in 2025 at "European Journal of Medical Research"

DOI: 10.1186/s40001-025-02776-0

Abstract: Pulmonary arterial hypertension (PAH) is currently an irreversible disease, with many patients eventually progressing to right heart failure, severely affecting their quality of life and posing a life-threatening risk. Percutaneous atrial septostomy was first performed… read more here.

Keywords: atrial septostomy; arterial hypertension; patients pah; pulmonary arterial ... See more keywords

The direct and indirect health care costs associated with pulmonary arterial hypertension among commercially insured patients in the United States.

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Published in 2022 at "Journal of managed care & specialty pharmacy"

DOI: 10.18553/jmcp.2022.28.6.608

Abstract: BACKGROUND: Pulmonary arterial hypertension (PAH) is a rare, progressive, and fatal disease associated with considerable overall clinical and economic burden. Although the direct health care costs of PAH have been well described, there are few… read more here.

Keywords: health; patients pah; period; care costs ... See more keywords

Childhood Trauma in Patients With PAH—Prevalence, Impact on QoL, and Mental Health—A Preliminary Report

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Published in 2022 at "Frontiers in Psychiatry"

DOI: 10.3389/fpsyt.2022.812862

Abstract: Background/Objective Child maltreatment is associated with increased risk of psychological consequences, contributes to morbidity and has long lasting effects on mental health and quality of life. Child maltreatment has not been assessed in patients with… read more here.

Keywords: patients pah; impact; child maltreatment; maltreatment ... See more keywords