Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2017.5818
Abstract: Importance Myelofibrosis is a hematologic malignancy characterized by splenomegaly and debilitating symptoms. Thrombocytopenia is a poor prognostic feature and limits use of Janus kinase 1 (JAK1)/Janus kinase 2 (JAK2) inhibitor ruxolitinib. Objective To compare the… read more here.
Keywords: patients patients; pacritinib; including ruxolitinib; bat ... See more keywords
Oral microbiomes of patients with infective endocarditis (IE): a comparative pilot study of IE patients, patients at risk for IE and healthy controls
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oral Microbiology"
DOI: 10.1080/20002297.2022.2144614
Abstract: ABSTRACT Background Infective endocarditis (IE) is an uncommon disease with high morbidity and mortality rates, which often develops from oral bacterial species entering circulation. Objective We compared oral microbiome profiles of three groups: IE patients… read more here.
Keywords: infective endocarditis; healthy controls; risk healthy; oral microbiomes ... See more keywords
P14.105 High incidence of brain metastases in lung cancer patients at the time of primary diagnosis
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz126.340
Abstract: Brain metastases (BM) affect 8%-10% of all cancer patients and 40% of patients with metastatic cancer. The majority of BM originate from lung cancer (40%-50%), breast cancer (15%-25%), and melanoma (5%-20%). Total incidence proportions percentage… read more here.
Keywords: brain metastases; patients patients; lung cancer; cancer ... See more keywords
Perioperative and Periprocedural anesthetic management of opioid tolerant patients and patients with active and medically treated opioid use disorder
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Anaesthesiology"
DOI: 10.1097/aco.0000000000001157
Abstract: Purpose of review The increasing prevalence of opioid tolerant individuals, in combination with the expanding scope and utilization of nonoperating room anesthesia (NORA) necessitates ongoing investigation into best clinical practice for managing surgical/procedural pain in… read more here.
Keywords: tolerant patients; opioid tolerant; opioid; opioid use ... See more keywords
To transfuse or not transfuse: an intensive appraisal of red blood cell transfusions in the ICU
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000460
Abstract: Purpose of review This review is a critical appraisal of the current data comparing restrictive vs. liberal transfusion strategies for patients who are critically ill in ICUs. We focus on four subsets of critically ill… read more here.
Keywords: patients patients; ill patients; transfuse; transfusion ... See more keywords
Continuous low‐dose gemcitabine in primary cutaneous T cell lymphoma: A retrospective study
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DOI: 10.1111/dth.15482
Abstract: The aim of our retrospective study was to evaluate the efficacy of a continuous therapy with a lower dosage of gemcitabine compared to those usually administered in patients with cutaneous T cell lymphomas (CTCL). Twenty‐two… read more here.
Keywords: dose gemcitabine; retrospective study; gemcitabine; cutaneous cell ... See more keywords
Necrotising fasciitis or pyoderma gangrenosum: A fatal dilemma
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DOI: 10.1111/iwj.13196
Abstract: Necrotising fasciitis (NF) is mostly a polymicrobial, severe soft tissue infection that progresses rapidly, penetrating through the subcutaneous tissue to the fascial planes and the muscles. The pyoderma gangrenosum (PG), on the other hand, is… read more here.
Keywords: fasciitis; patients patients; risk; tissue ... See more keywords
The use of cryopreserved platelets in the treatment of polytraumatic patients and patients with massive bleeding
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DOI: 10.1111/trf.15177
Abstract: The short shelf‐life of fresh platelets limits their efficient inventory management and availability during a massive transfusion protocol. Risk of insufficient availability can be mitigated by building an inventory of cryopreserved platelets (CPs). read more here.
Keywords: patients patients; use cryopreserved; polytraumatic patients; cryopreserved platelets ... See more keywords
Coccidioidomycosis Complement Fixation Titer Trends in the Age of Antifungals
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01318-18
Abstract: Coccidioidomycosis is associated with a broad spectrum of illness severity, ranging from asymptomatic or self-limited pulmonary infection to life-threatening manifestations of disseminated disease. Serologic studies before the widespread availability of antifungals established current understanding of… read more here.
Keywords: complement fixation; patients patients; titer trends; coccidioidomycosis ... See more keywords
Predisposing factors of childhood Henoch-Schönlein purpura in Anhui province, China
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Investigative Medicine"
DOI: 10.1136/jim-2018-000906
Abstract: Henoch-Schönlein purpura (HSP) is a common autoimmune vasculitis in childhood. The detailed pathogenesis of HSP is still unclear, whereas several types of predisposing factors have been proved to be the initial step. The objectives of… read more here.
Keywords: patients patients; henoch sch; predisposing factors; nlein purpura ... See more keywords
743 High levels of stromal tumor infiltrating lymphocytes, CD3, CD8 cells & Immunoscore® are associated with pathological CR and time to progression in TNBC patients undergoing neo-adjuvant chemotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0743
Abstract: Background The presence of high levels of stromal tumor infiltrating lymphocytes (TILs) has been associated with better prognosis in early triple-negative breast cancer (TNBC). The Immunoscore® (IS) is a prognostic tool, which categorizes the densities… read more here.
Keywords: patients patients; tnbc patients; cd8; high levels ... See more keywords