Articles with "patients pbc" as a keyword



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Patterns of serum lipids derangements and cardiovascular risk assessment in patients with primary biliary cholangitis.

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Published in 2019 at "Annals of hepatology"

DOI: 10.1016/j.aohep.2019.07.006

Abstract: INTRODUCTION AND OBJECTIVES Primary biliary cholangitis (PBC) is a chronic cholestatic autoimmune disease that disrupts the cholesterol metabolism. Our aim was to investigate the frequency of dyslipidemias and to evaluate the risk of cardiovascular events… read more here.

Keywords: patients pbc; risk; cardiovascular risk; primary biliary ... See more keywords
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The association of histological progression with biochemical response to ursodeoxycholic acid in primary biliary cholangitis

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Published in 2020 at "Hepatology Research"

DOI: 10.1111/hepr.13593

Abstract: Primary biliary cholangitis (PBC) is currently diagnosed at an early stage; therefore, the number of patients with PBC without symptoms at the time of diagnosis is increasing. However, up to 30% of patients with PBC… read more here.

Keywords: primary biliary; patients pbc; response; disease ... See more keywords

Imbalanced distribution of group 2 innate lymphoid cells (ILCs) and ILC precursors in peripheral blood of patients with primary biliary cholangitis.

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Published in 2022 at "Scandinavian journal of immunology"

DOI: 10.1111/sji.13166

Abstract: Innate lymphoid cells (ILCs), a novel group of innate immune cells, play a key role in the early immune response via rapidly reacting to signals expressed by tissue-resident cells. ILCs contribute to some autoimmune diseases.… read more here.

Keywords: group; cells ilcs; patients pbc; ilcp ilc2 ... See more keywords
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Measurement properties of the PBC-40 and PBC-27: a Dutch validation study

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Published in 2021 at "BMJ Open Gastroenterology"

DOI: 10.1136/bmjgast-2021-000758

Abstract: Objective Patients with primary biliary cholangitis (PBC) have an impaired health-related quality of life (HRQoL). Practice guidelines recommend evaluating the HRQoL in all patients with PBC. The aim of this study was to assess the… read more here.

Keywords: pbc pbc; study; patients pbc; pbc ... See more keywords
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Fibrates for the treatment of pruritus in primary biliary cholangitis: a systematic review and meta-analysis.

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Published in 2021 at "Annals of palliative medicine"

DOI: 10.21037/apm-21-1304

Abstract: BACKGROUND This meta-analysis aimed to evaluate the effectiveness of fibrates in the treatment of pruritus in patients with primary biliary cholangitis (PBC), so as to guide the clinical treatment of such cases. METHODS Searches of… read more here.

Keywords: fibrates treatment; patients pbc; analysis; pruritus ... See more keywords
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CXCL12-CXCR4-Mediated Chemotaxis Supports Accumulation of Mucosal-Associated Invariant T Cells Into the Liver of Patients With PBC

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.578548

Abstract: Objectives: To explore the potential role of CD3+CD8+CD161high TCRVα7.2+ mucosal-associated invariant T (MAIT) cells in the pathogenesis of primary biliary cholangitis (PBC). Methods: We enrolled 55 patients with PBC, 69 healthy controls (HCs), and 8… read more here.

Keywords: patients pbc; mediated chemotaxis; associated invariant; mait cells ... See more keywords
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Disease predisposition of human leukocyte antigen class II genes influences the gut microbiota composition in patients with primary biliary cholangitis

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.984697

Abstract: Background The human leukocyte antigen (HLA) susceptibility gene is the main genetic risk factor for primary biliary cholangitis (PBC). The prognosis of patients with PBC is linked to gut microbiota dysbiosis. However, whether the HLA… read more here.

Keywords: gut microbiota; hla; fhrac positive; class ... See more keywords
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Macrophage Activation Markers Predict Liver-Related Complications in Primary Biliary Cholangitis

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23179814

Abstract: Primary biliary cholangitis (PBC) has a wide variation in clinical presentation and course. There is no significant correlation between these symptoms and the disease stage, although patients with more advanced stages generally have more symptoms.… read more here.

Keywords: macrophage activation; related complications; primary biliary; biliary cholangitis ... See more keywords