Assessment of Quality of Life Among Patients With Recurrent Clostridioides difficile Infection Treated with Investigational Oral Microbiome Therapeutic SER-109
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.53570
Abstract: This secondary analysis of a randomized clinical trial examines the association of SER-109 with health-related quality of life in 182 patients with recurrent Clostridioides difficile infection in the US and Canada. read more here.
Keywords: recurrent clostridioides; clostridioides difficile; difficile infection; patients recurrent ... See more keywords
Validation of brief symptom indexes among patients with recurrent or metastatic squamous cell carcinoma of the head and neck: A trial of the ECOG‐ACRIN Cancer Research Group (E1302)
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DOI: 10.1002/cam4.3506
Abstract: Patients with advanced head and neck cancer have identified pain, fatigue, and difficulties swallowing, breathing, and communicating as high‐priority disease‐related symptoms. The Functional Assessment of Cancer Therapy‐Head and Neck Symptom Index‐10 (FHNSI‐10) assesses these symptoms.… read more here.
Keywords: head; among patients; brief symptom; cancer ... See more keywords
A phase 1 and randomized, placebo‐controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872
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DOI: 10.1002/cncr.32340
Abstract: Src signaling is markedly upregulated in patients with invasive glioblastoma (GBM) after the administration of bevacizumab. The Src family kinase inhibitor dasatinib has been found to effectively block bevacizumab‐induced glioma invasion in preclinical models, which… read more here.
Keywords: bevacizumab; placebo controlled; randomized placebo; phase randomized ... See more keywords
Optimum selection criteria for secondary cytoreductive surgery in patients with recurrent epithelial ovarian cancer: A multicenter study from the Gynecologic Oncology Research Investigators coLLaborAtion group (GORILLA-3001).
Sign Up to like & getrecommendations! Published in 2023 at "Journal of surgical oncology"
DOI: 10.1002/jso.27303
Abstract: BACKGROUND To identify those most likely to benefit from secondary cytoreductive surgery (SCS), we evaluated the survival outcomes and factors predictive of prognosis in patients with recurrent ovarian cancer. METHODS We retrospectively reviewed the medical… read more here.
Keywords: oncology; surgery; ovarian cancer; patients recurrent ... See more keywords
Dynamic contrast-enhanced MRI may be helpful to predict response and prognosis after bevacizumab treatment in patients with recurrent high-grade glioma: comparison with diffusion tensor and dynamic susceptibility contrast imaging
Sign Up to like & getrecommendations! Published in 2021 at "Neuroradiology"
DOI: 10.1007/s00234-021-02693-z
Abstract: We aimed to evaluate the utility of diffusion tensor imaging (DTI), dynamic contrast-enhanced (DCE), and dynamic susceptibility contrast (DSC) imaging for stratifying bevacizumab treatment outcomes in patients with recurrent high-grade glioma. Fifty-three patients with recurrent… read more here.
Keywords: bevacizumab treatment; contrast; high grade; grade glioma ... See more keywords
A phase 1 trial of intravenous liposomal irinotecan in patients with recurrent high-grade glioma
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DOI: 10.1007/s00280-017-3247-3
Abstract: PurposePreclinical activity of irinotecan has been seen in glioma models, but only modest efficacy has been noted in clinical studies, perhaps related to drug distribution and/or pharmacokinetic limitations. In preclinical testing, irinotecan liposome injection (nal-IRI)… read more here.
Keywords: glioma; grade glioma; high grade; patients recurrent ... See more keywords
Therapy-free interval has prognostic value in patients with recurrent cervical cancer treated with chemotherapy following definitive concurrent chemoradiotherapy: methodological issues
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4629-9
Abstract: We were interested to read the paper by Kozaki and colleagues that was published in Archives of Gynecology and Obstetrics [1]. The authors aimed to examine the efficacy of the chemotherapy, predictive factors for the… read more here.
Keywords: chemotherapy; free interval; value; model ... See more keywords
Factors associated with post-relapse survival in patients with recurrent cervical cancer: the value of the inflammation-based Glasgow Prognostic Score
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-018-4993-0
Abstract: AbstractPurposeThe aim of the present study was to assess the value of the Glasgow Prognostic Score (GPS) as a prognostic tool for predicting post-relapse survival (PRS) in patients with recurrent cervical cancer.MethodsWe retrospectively evaluated the… read more here.
Keywords: prs; recurrent cervical; cervical cancer; relapse ... See more keywords
Nivolumab for patients with recurrent glioblastoma progressing on bevacizumab: a retrospective case series
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DOI: 10.1007/s11060-017-2466-0
Abstract: A single institution retrospective evaluation of nivolumab following disease progression on bevacizumab in adults with recurrent glioblastoma (GBM) with an objective of determining progression free survival (PFS). There is no accepted therapy for recurrent GBM… read more here.
Keywords: gbm; nivolumab; recurrent glioblastoma; patients recurrent ... See more keywords
Large volume re-irradiation for recurrent meningioma with pulsed reduced dose rate radiotherapy
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DOI: 10.1007/s11060-018-03011-z
Abstract: PurposeMeningiomas comprise up to 30% of primary brain tumors. The majority of meningioma patients enjoy high rates of control after conventional therapies. However, patients with recurrent disease previously treated with radiotherapy have few options for… read more here.
Keywords: recurrent meningioma; patients recurrent; pulsed reduced; dose rate ... See more keywords
Retrospective study of nivolumab for patients with recurrent high grade gliomas
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DOI: 10.1007/s11060-018-2907-4
Abstract: IntroductionPatients with recurrent high-grade gliomas (HGG) have limited treatment options. HGG utilize the PD-1 pathway to evade immune responses. Checkpoint inhibitors have demonstrated safety and clinical activity in patients with recurrent glioblastoma. We explored the… read more here.
Keywords: high grade; received nivolumab; grade gliomas; patients recurrent ... See more keywords