Assessment of Clinical Response to Anifrolumab in Patients With Refractory Discoid Lupus Erythematosus.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0175
Abstract: This case series examines the efficacy of anifrolumab as a therapeutic option for patients with lupus erythematosus. read more here.
Keywords: clinical response; patients refractory; anifrolumab patients; response anifrolumab ... See more keywords
PRospective REgistry of PAtients in REfractory cardiogenic shock—The PREPARE CardShock registry
Sign Up to like & getrecommendations! Published in 2022 at "Catheterization and Cardiovascular Interventions"
DOI: 10.1002/ccd.30327
Abstract: Cardiogenic shock (CS) is a hemodynamically complex multisystem syndrome associated with persistently high morbidity and mortality. As CS is characterized by progressive failure to provide adequate systemic perfusion, supporting end‐organ perfusion using mechanical circulatory support… read more here.
Keywords: patients refractory; registry; registry patients; prospective registry ... See more keywords
Sacral neuromodulation in patients with refractory overactive bladder symptoms after failed Botulinum toxin therapy: Results in a large cohort of patients
Sign Up to like & getrecommendations! Published in 2021 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24670
Abstract: Sacral neuromodulation (SNM) and Botulinum toxin A (BoNT‐A) injections are well‐known third‐line treatment options in patients with refractory overactive bladder (OAB). Our aim is to evaluate the success rate of SNM in patients who received… read more here.
Keywords: overactive bladder; patients refractory; sacral neuromodulation; botulinum toxin ... See more keywords
Long-term experience of atrioventricular node ablation in patients with refractory atrial arrhythmias
Sign Up to like & getrecommendations! Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01536-5
Abstract: Atrial fibrillation and other atrial tachyarrhythmias are increasing with age and concomitant morbidity. First options in symptomatic patients are drug treatment and catheter ablation. Nevertheless, a considerable number of patients suffer from refractory atrial tachyarrhythmias… read more here.
Keywords: atrioventricular node; ablation; atrial tachyarrhythmias; refractory atrial ... See more keywords
Characterization of Patients With Refractory or Unexplained Chronic Cough Participating in a Phase 2 Clinical Trial of the P2X3-Receptor Antagonist Gefapixant
Sign Up to like & getrecommendations! Published in 2021 at "Lung"
DOI: 10.1007/s00408-021-00437-7
Abstract: This analysis assesses clinical characteristics of patients with refractory chronic cough (RCC) or unexplained chronic cough (UCC) enrolled in a phase 2 study to better understand this patient population. Patients with RCC/UCC lasting for ≥ 1 year… read more here.
Keywords: phase; unexplained chronic; cough; patients refractory ... See more keywords
A prospective cross-sectional study of serum IL-17A in antisynthetase syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05013-7
Abstract: The pro-inflammatory interleukin (IL)-17A serum has been characterized in several systemic autoimmune diseases, but not in antisynthetase syndrome (ASS). Therefore, the present study aims firstly to assess the serum level of the IL-17A in patients… read more here.
Keywords: levels 17a; patients ass; serum; serum levels ... See more keywords
Effectiveness of ketogenic diet in treatment of patients with refractory chronic migraine
Sign Up to like & getrecommendations! Published in 2021 at "Neurological Sciences"
DOI: 10.1007/s10072-021-05078-5
Abstract: Ketogenic diet (KD) is based on restriction of carbohydrate intake. Metabolism is forced to obtain energy starting from β-oxidation of fatty acids which, turned into ketone bodies, can also be used by central nervous system… read more here.
Keywords: migraine; treatment; patients refractory; chronic migraine ... See more keywords
Phase II study of doxorubicin and thalidomide in patients with refractory aggressive fibromatosis
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0542-0
Abstract: SummaryBackground To evaluate the efficacy and safety of doxorubicin (ADM) combined with thalidomide (THA) as a first-line treatment for patients with refractory aggressive fibromatosis (AF). Patients and Methods Eligible patients were treated with ADM 30 mg/m2… read more here.
Keywords: study doxorubicin; refractory aggressive; patients refractory; phase study ... See more keywords
The effectiveness and safety of glecaprevir/pibrentasvir in chronic hepatitis C patients with refractory factors in the real world: a comprehensive analysis of a prospective multicenter study
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology International"
DOI: 10.1007/s12072-020-10019-z
Abstract: Background Direct-acting anti-virals (DAAs) have markedly improved the effectiveness of anti-viral therapy for chronic hepatitis C (CHC) patients. In a phase III trial in Japan, treatment with the NS3/4A protease inhibitor glecaprevir and the NS5A… read more here.
Keywords: ckd stage; safety; genotype; refractory factors ... See more keywords
Use of the Impella 5.0 Micro-Axial Flow Device in Refractory Cardiogenic Shock - A Single Center Experience
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2019.07.530
Abstract: Introduction Patients with refractory cardiogenic shock have a mortality in excess of 80%. The use of percutaneous mechanical circulatory support devices to bridge patients with refractory cardiogenic shock to definitive therapy has steadily increased, although… read more here.
Keywords: impella; refractory cardiogenic; cardiogenic shock; center ... See more keywords
Phase 1 clinical trial of adoptive immunotherapy using "off-the-shelf" activated natural killer cells in patients with refractory and relapsed acute myeloid leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2017.07.008
Abstract: BACKGROUND AIMS Activated NK cells (aNK) generated by expansion of a human interleukin-2-dependent NK cell line (NK-92) were shown to mediate strong anti-leukemia activity. This phase 1 study evaluated feasibility, safety, and activity of aNK… read more here.
Keywords: ank cells; cell; refractory relapsed; patients refractory ... See more keywords