Survival trends for patients with retinoblastoma between 2000 and 2018: What has changed?
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DOI: 10.1002/cam4.5406
Abstract: Retinoblastoma (RB) is the most common primary intraocular cancer of childhood. Over the last few decades, a variety of techniques and treatment modalities emerged that improved the survival and ocular salvage rate of patients with… read more here.
Keywords: survival trends; retinoblastoma 2000; patients retinoblastoma; 2000 2018 ... See more keywords
Genetic screening in Iranian patients with retinoblastoma
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DOI: 10.1038/eye.2016.289
Abstract: PurposeThe most common intraocular tumor in childhood, retinoblastoma, is largely associated with mutations in the RB1 gene. In the most comprehensive RB1 screening in Iran, we evaluated the RB1 mutations in 106 patients with retinoblastoma,… read more here.
Keywords: genetic screening; retinoblastoma; iranian patients; patients retinoblastoma ... See more keywords
Clinical, epidemiological, and therapeutic profile of patients with a retinoblastoma diagnosis experience in the Costa Rica National Children’s Hospital Oncology Unit from January 2009 to December 2015
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DOI: 10.3332/ecancer.2017.754
Abstract: Introduction Retinoblastoma represents only 3% of paediatric cancers, but it is the most prevalent intraocular tumour in this population. It develops in the retina as a primitive neuroectodermal tumour that affects development during gestation. The… read more here.
Keywords: retinoblastoma diagnosis; treatment; patients retinoblastoma; costa rica ... See more keywords
High levels of global genome methylation in patients with retinoblastoma
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DOI: 10.3892/ol.2020.11613
Abstract: Retinoblastoma is a tumor of the embryonic neural retina in young children. The DNA methyltransferase 1 (DNMT1) gene has been demonstrated to be transcriptionally activated in cells lacking retinoblastoma 1 (RB1). Thus, there is a… read more here.
Keywords: methylation; levels global; genome methylation; patients retinoblastoma ... See more keywords