Pulse dose steroid experience among hospitalized patients with systemic lupus erythematosus: a single-center feasibility study
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DOI: 10.1007/s10067-021-05644-4
Abstract: Introduction/objectives: Pulse intravenous (IV) methylprednisolone (MEP) is often used for severe SLE manifestations requiring hospitalization. However, the accuracy of pulse dose documentation extracted from the electronic health record (EHR) is unknown. We assessed the feasibility… read more here.
Keywords: among hospitalized; icd code; feasibility study; ehr ... See more keywords
Analysis of the free fatty acid metabolome in the plasma of patients with systemic lupus erythematosus and fever
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DOI: 10.1007/s11306-017-1308-6
Abstract: IntroductionSystemic lupus erythematosus (SLE) is a multifactorial autoimmune disease with heterogeneous clinical manifestations mediated by immune dysregulation.ObjectivesWe aimed to analyze the metabolomic differences in free fatty acids (FFAs) between patients with SLE and healthy controls… read more here.
Keywords: lupus erythematosus; free fatty; disease; plasma patients ... See more keywords
Drusen-like Deposits in Young Adults Diagnosed With Systemic Lupus Erythematosus.
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DOI: 10.1016/j.ajo.2016.11.014
Abstract: PURPOSE To determine the prevalence of drusen-like deposits (DLDs) and choroidal changes in patients with systemic lupus erythematosus (SLE), with or without glomerulonephritis; and to correlate ocular findings with systemic features. DESIGN Case-control study. METHODS… read more here.
Keywords: systemic lupus; lupus erythematosus; like deposits; drusen like ... See more keywords
Systemic lupus erythematosus: iNKT cells guard the heart against disease
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DOI: 10.1038/nrrheum.2016.216
Abstract: Invariant natural killer T (iNKT) cells might have an atheroprotective role in patients with systemic lupus erythematosus (SLE) who have asymptomatic atherosclerotic plaques, according to new research. “For the first time, we describe a link… read more here.
Keywords: systemic lupus; lupus erythematosus; disease; inkt cells ... See more keywords
The Impact of The COVID-19 Pandemic On SLE.
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DOI: 10.1093/mr/road030
Abstract: Little is known about the association between coronavirus disease 2019 [COVID-19] and autoimmune diseases, especially for systemic lupus erythematosus [SLE]. SLE patients meet with a throng of questions during the pandemic, including minimize the risk… read more here.
Keywords: sle; patients sle; impact covid; infection ... See more keywords
The expression of Ets-1 and Fli-1 is associated with interferon-inducible genes in peripheral blood mononuclear cells from Japanese patients with systemic lupus erythematosus
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DOI: 10.1097/md.0000000000031522
Abstract: Transcription factors E26 transformation-specific-1 (Ets-1) and Friend leukemia insertion site-1 (Fli-1) and type I interferon (IFN) have been implicated in systemic lupus erythematosus (SLE). We examined the expression of these genes in peripheral blood mononuclear… read more here.
Keywords: ets fli; patients sle; japanese patients; expression ... See more keywords
AHR/TET2/NT5E axis downregulation is associated with the risk of systemic lupus erythematosus and its progression
Sign Up to like & getrecommendations! Published in 2022 at "Immunology"
DOI: 10.1111/imm.13600
Abstract: The prognosis of systemic lupus erythematosus (SLE) is unpredictable. This study aimed to examine the regulatory mechanism of the AHR/TET2/NT5E pathway during SLE progression. The AHR, TET2 and NT5E expression levels were examined in T… read more here.
Keywords: patients sle; ahr tet2; expression; systemic lupus ... See more keywords
Association of leptin and leptin receptor gene polymorphisms with systemic lupus erythematosus in a Chinese population
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DOI: 10.1111/jcmm.13093
Abstract: To explore the association of LEP and leptin receptor (LEPR) gene single‐nucleotide polymorphisms (SNPs) with susceptibility to systemic lupus erythematosus (SLE) in a Chinese population. Four LEP SNPs (rs11761556, rs12706832, rs2071045 and rs2167270) and nine… read more here.
Keywords: systemic lupus; leptin receptor; lupus erythematosus; association ... See more keywords
AB0479 The role of antibodies to xanthine oxidase and adenosine deaminase in the development of anti-phospholipid syndrome in patients with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.4728
Abstract: Objectives The aim of the research was to study the processes of formation of antibodies to the enzyme purine metabolism (PM) - xanthine oxidase (XO) and adenosine deaminase (ADA) - in patients with systemic lupus… read more here.
Keywords: xanthine oxidase; class; anti; apl ... See more keywords
SAT0227 Health care utilization and costs of systemic lupus erythematosus (SLE) in the united states: systematic review
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DOI: 10.1136/annrheumdis-2017-eular.5224
Abstract: Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects as many as 518 persons per 100,000 people in the United States and Europe. However, much of our current knowledge on SLE health… read more here.
Keywords: health care; utilization; united states; care ... See more keywords
OP0196 IMBALANCE BETWEEN MEMORY TH1 AND TH1-TREG CELLS DEPENDS ON DIFFERENTIAL REGULATION OF CELL METABOLISM IN PATIENTS WITH SLE
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DOI: 10.1136/annrheumdis-2019-eular.3409
Abstract: Background T helper 1 (Th1) cells play an important role in Systemic Lupus Erythematosus (SLE). However, which abnormalities generated in Th1 cells may be related to the pathogenesis of SLE remains elusive. “Immunometabolism” has recently… read more here.
Keywords: treg cells; th1 cells; th1 treg; th1 ... See more keywords