Patients with SMARCA4-deficient thoracic sarcoma and severe skeletal-related events.
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DOI: 10.1016/j.lungcan.2019.03.029
Abstract: OBJECTIVES SMARCA4-deficient thoracic sarcoma(DTS) is a recently identified new entity of thoracic malignancies characterized by inactivation of SMARCA4. Patients with SMARCA4-DTS have a particulary aggresive clinical course and no effective treatments. However, the detailed clinical… read more here.
Keywords: deficient thoracic; smarca4; patients smarca4; thoracic sarcoma ... See more keywords
STK11/KEAP1 co-mutations in SMARCA4-mutant advanced non-small cell lung cancer: genetic characteristics and impact on immunotherapy efficacy
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DOI: 10.21037/tlcr-2025-305
Abstract: Background The impact of STK11/KEAP1 co-mutations on the efficacy of immunotherapy in patients with SMARCA4-mutant advanced non-small cell lung cancer (NSCLC) remains incompletely understood. Our aim was to investigate the effects of STK11/KEAP1 co-mutations on… read more here.
Keywords: mpfs1 months; keap1 mutations; stk11 keap1; smarca4 mutant ... See more keywords