Urinary Pentosidine levels negatively associates with trabecular bone scores in patients with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2017 at "Osteoporosis International"
DOI: 10.1007/s00198-017-4359-7
Abstract: SummaryPentosidine levels were higher in diabetic patients with vertebral fractures. Trabecular bone scores were negatively associated with pentosidine levels in diabetic patients only. Our results provide further evidence that AGEs are associated with the pathogenesis… read more here.
Keywords: trabecular bone; pentosidine levels; patients t2dm; pentosidine ... See more keywords
Pharmacokinetics, Pharmacodynamics, and Safety of Dulaglutide After Single or Multiple Doses in Chinese Healthy Subjects and Patients with T2DM: A Randomized, Placebo-Controlled, Phase I Study
Sign Up to like & getrecommendations! Published in 2021 at "Advances in Therapy"
DOI: 10.1007/s12325-021-01921-5
Abstract: This study evaluated the pharmacokinetics, pharmacodynamics, and safety of a single dulaglutide dose in Chinese healthy subjects and of multiple dulaglutide doses in Chinese patients with type 2 diabetes mellitus (T2DM). This two-part, double-blind, placebo-controlled… read more here.
Keywords: safety; study; healthy subjects; pharmacokinetics pharmacodynamics ... See more keywords
Nutrient sensing pathway genes expression dysregulated in patients with T2DM and coronary artery disease.
Sign Up to like & getrecommendations! Published in 2019 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2019.03.036
Abstract: AIMS Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder and its prevalence is rapidly increasing worldwide. Patients with T2DM suffer from an increased risk of vascular complications. Of these, the development of coronary… read more here.
Keywords: cad t2dm; nutrient sensing; expression; patients t2dm ... See more keywords
Skin autofluorescence is associated with vascular complications in patients with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of diabetes and its complications"
DOI: 10.1016/j.jdiacomp.2018.06.009
Abstract: AIMS Tissue accumulatedadvanced glycation end products (AGEs) can be evaluated non-invasively by an autofluorescence reader as skin autofluorescence (skin AF)·The present study investigated whether skin AF is associated with diabetic micro- and macroangiopathies in Japanese… read more here.
Keywords: patients type; skin autofluorescence; japanese patients; type diabetes ... See more keywords
The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Medicina clinica"
DOI: 10.1016/j.medcli.2021.06.028
Abstract: BACKGROUND Type 2 diabetes mellitus (T2DM) is a progressive meta-inflammatory disorder, which induce micro and macrovascular complications. Resveratrol is a nutraceutical known to have antioxidant and anti-inflammatory properties. It improves insulin resistance; however, no clear… read more here.
Keywords: review meta; systematic review; meta; patients t2dm ... See more keywords
MIF 173 G>C variation was associated with depressive disorder in type 2 diabetes in an Iranian population
Sign Up to like & getrecommendations! Published in 2019 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2019.03.011
Abstract: BACKGROUND Type 2 diabetes mellitus (T2DM) is a continuous metabolic disease linked with increased rate of mortality and morbidity. High levels of glucose can damage organs including kidneys, eyes, and the nervous system. Individuals with… read more here.
Keywords: depression; mif 173; 173 variation; type diabetes ... See more keywords
Drugs That Improve Cardiovascular Prognosis in Diabetes and Are Not Yet Used by Cardiologists.
Sign Up to like & getrecommendations! Published in 2018 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2018.08.012
Abstract: Type 2 diabetes mellitus (T2DM) is currently one of the most prevalent health problems worldwide. According to estimated data, 246 million people have T2DM globally, and this figure may double by 2025. If we concentrate… read more here.
Keywords: benefit; prognosis; treatment; disease ... See more keywords
p62 — a new metabolic tumour suppressor
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Endocrinology"
DOI: 10.1038/s41574-018-0018-0
Abstract: The gut microbiota ferments dietary carbohydrates to produce short-chain fatty acids (SCFAs). In patients with type 2 diabetes mellitus (T2DM), there is a decrease in SCFA production and previous studies have shown that a high-fibre… read more here.
Keywords: high fibre; p62 new; group; fibre diet ... See more keywords
Renoprotective effects of dulaglutide in patients with T2DM and CKD
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DOI: 10.1038/s41581-018-0055-x
Abstract: The AWARD-7 trial shows that the glucagon-like peptide 1 (GLP1) receptor agonist dulaglutide, which is not cleared by the kidney, seems to be renoprotective, ameliorates albuminuria and slows estimated glomerular filtration rate decline in patients… read more here.
Keywords: effects dulaglutide; renoprotective effects; t2dm ckd; patients t2dm ... See more keywords
The severity and clinical characteristics of COVID-19 among patients with type 2 diabetes mellitus in Jazan, Saudi Arabia
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029215
Abstract: Abstract Background: The objectives of the current study were to assess the severity and clinical characteristics of coronavirus disease 2019 (COVID-19) among Saudi adults with type 2 diabetes mellitus (T2DM) in Jazan region, Saudi Arabia.… read more here.
Keywords: patients t2dm; covid patients; severity clinical; covid ... See more keywords
Metformin upregulates mitophagy in patients with T2DM: A randomized placebo‐controlled study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14834
Abstract: Impaired mitochondrial autophagy (mitophagy) and NLRP3 inflammasome activation have been incriminated in the pathogenesis of T2DM. Metformin besides being an insulin sensitizer also induces autophagy; however, its effect on mitophagy and NLRP3 activation in patients… read more here.
Keywords: placebo; upregulates mitophagy; metformin upregulates; patients t2dm ... See more keywords