A new paradigm for leprosy diagnosis based on host gene expression.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS pathogens"
DOI: 10.1371/journal.ppat.1009972
Abstract: Transcriptional profiling is a powerful tool to investigate and detect human diseases. In this study, we used bulk RNA-sequencing (RNA-Seq) to compare the transcriptomes in skin lesions of leprosy patients or controls affected by other… read more here.
Keywords: paucibacillary leprosy; paradigm leprosy; diagnosis based; leprosy diagnosis ... See more keywords
Utility of Multi-target Nested PCR and ELISPOT Assays for the Detection of Paucibacillary Leprosy: A Possible Conclusion of Clinical Laboratory Misdiagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.814413
Abstract: The diagnosis of paucibacillary (PB) leprosy often possesses a diagnostic challenge, especially for pure neuritic and lesser skin lesions with the zero bacillary load, requiring a sensitive and accurate diagnostic tool. We have included 300… read more here.
Keywords: leprosy cases; pcr elispot; paucibacillary leprosy; clinical laboratory ... See more keywords
Dermoscopy and clinicopathology features in diagnosing paucibacillary leprosy: Case series
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Mycobacteriology"
DOI: 10.4103/ijmy.ijmy_113_22
Abstract: A wide variety of leprosy clinical manifestations poses an early diagnostic challenge. Currently, various diagnostic modalities have been developed to optimize the definite diagnostic of leprae. Leprosy diagnosis was established based on the presence of… read more here.
Keywords: clinicopathology features; features diagnosing; dermoscopy clinicopathology; paucibacillary leprosy ... See more keywords