Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex.
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DOI: 10.1016/j.celrep.2022.110673
Abstract: RNA activation (RNAa) is an uncharacterized mechanism of transcriptional activation mediated by small RNAs, such as microRNAs (miRNAs). A critical issue in RNAa research is that it is difficult to distinguish between changes in gene… read more here.
Keywords: rnaa; paused pol; post transcriptional; transcriptional regulation ... See more keywords