Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease
Sign Up to like & getrecommendations! Published in 2020 at "Human Genetics"
DOI: 10.1007/s00439-020-02212-9
Abstract: Paired-box (PAX) genes encode a family of highly conserved transcription factors found in vertebrates and invertebrates. PAX proteins are defined by the presence of a paired domain that is evolutionarily conserved across phylogenies. Inclusion of… read more here.
Keywords: tissue specific; tissue; pax proteins; variant expression ... See more keywords
Are Pax proteins potential therapeutic targets in kidney disease and cancer?
Sign Up to like & getrecommendations! Published in 2018 at "Kidney international"
DOI: 10.1016/j.kint.2018.01.025
Abstract: Pax genes encode developmental regulators that are expressed in a variety of tissues and control critical events in morphogenesis. In the kidney, Pax2 and Pax8 are expressed in embryonic development and in specific renal diseases… read more here.
Keywords: proteins potential; pax proteins; cancer; pax ... See more keywords