Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation
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DOI: 10.1038/s41598-019-40810-4
Abstract: A previously identified enhancer 10 kb upstream of the Aggrecan (Acan) gene (UE) can drive cartilage specific reporter expression in vivo. Here, we report that the paralogous transcription factors PAX1 and PAX9 differentially drive UE, depending… read more here.
Keywords: transactivation; sox9 driven; driven transactivation; upstream aggrecan ... See more keywords
Association and Effectiveness of PAX1 Methylation and HPV Viral Load for the Detection of Cervical High-Grade Squamous Intraepithelial Lesion
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DOI: 10.3390/pathogens12010063
Abstract: Background: PAX1 methylation (PAX1m) and HPV viral load (VL) have been reported to detect cervical high-grade squamous intraepithelial lesions (HSIL), but the relationship between them is unclear. This study aimed to evaluate the correlation between… read more here.
Keywords: pax1 methylation; hpv viral; cervical high; viral load ... See more keywords