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Missense Variants in PAX4 Are Associated with Early-Onset Diabetes in Chinese

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Published in 2020 at "Diabetes Therapy"

DOI: 10.1007/s13300-020-00960-5

Abstract: Introduction East Asians are more susceptible to early-onset diabetes than Europeans and exhibit reduced insulin secretion at earlier stages. PAX4 plays a critical role in the development of β-cells. The dysfunction-missense variants PAX4 R192H and… read more here.

Keywords: east asians; onset diabetes; early onset; pax4 r192h ... See more keywords