PAX7 Is a Sensitive Marker of Skeletal Muscle Differentiation in Rhabdomyosarcoma and Tumors With Rhabdomyosarcomatous Differentiation in the Female Genital Tract
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000799
Abstract: In the female genital tract, rhabdomyosarcoma may occur in “pure” form or as a heterologous constituent of a biphasic neoplasm such as carcinosarcoma or adenosarcoma. Discriminating rhabdomyosarcoma from its histologic mimics relies on confirmation of… read more here.
Keywords: pax7; rhabdomyosarcoma; differentiation; skeletal muscle ... See more keywords
Abstract 3022: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma indentity
Sign Up to like & getrecommendations! Published in 2021 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2021-3022
Abstract: Rhabdomyosarcoma (RMS) is an embryonal tumor resembling developing skeletal muscle and the most common pediatric soft-tissue sarcoma. RMS is molecularly defined by the presence or absence of a fusion oncoprotein corresponding with the histological subtypes… read more here.
Keywords: pax7; loss; core; skeletal muscle ... See more keywords