LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "paz" as a keyword



Photo by teveir from unsplash

Exploiting Click Chemistry for the Covalent Immobilization of Tetra (4-Propargyloxyphenoxy) Metallophthalocyanines onto Phenylazide-Grafted Gold Surfaces

Sign Up to like & get
recommendations! Published in 2017 at "Electrochimica Acta"

DOI: 10.1016/j.electacta.2017.09.115

Abstract: Abstract In this study, tetra-(4-propargyloxy)phenoxy phthalocyanines (MTPrOPhOPc) were covalently immobilized as thin films onto gold surfaces via click reaction. The gold electrode surfaces were pre-functionalized with phenylazide (Au-PAz) thin film using in-situ diazonium generation followed… read more here.

Keywords: gold surfaces; gold electrode; chemistry; paz ... See more keywords
Photo from wikipedia

How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for de Novo siRNA Guide Strand Surrogate Selection

Sign Up to like & get
recommendations! Published in 2019 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.8b00892

Abstract: The Argonaute-2 protein is part of the RNA-induced silencing complex (RISC) and anchors the guide strand of the small interfering RNA (siRNA). The 3'-end of the RNA contains two unpaired nucleotides (3'-overhang) that interact with… read more here.

Keywords: molecular interaction; energy profiling; paz; guide strand ... See more keywords
Photo from wikipedia

Insights into the effect of molecular crowding on the structure, interactions and functions of siRNA–PAZ complex through molecular dynamics studies

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2018.1498391

Abstract: Abstract siRNA molecules are well known to be involved in the post-transcriptional regulation of gene expression and play a key role in understanding the intricacies of eukaryotic gene regulation. While it is widely known that… read more here.

Keywords: paz complex; sirna paz; paz; molecular crowding ... See more keywords
Photo from wikipedia

PAZ domain is critical for spermatogenesis in chicken.

Sign Up to like & get
recommendations! Published in 2021 at "Animal biotechnology"

DOI: 10.1080/10495398.2021.2011742

Abstract: Piwi-like protein 1 (PIWIL1) plays a crucial role in stem cell proliferation, embryogenesis, growth, and development. We aimed to unravel the function of PIWIL1 and its Piwi/Argonaute/Zwille (PAZ) domain in chicken embryogenesis. The expression of… read more here.

Keywords: critical spermatogenesis; paz domain; domain critical; paz ... See more keywords
Photo from wikipedia

A randomized phase II trial of pazopanib (PAZ) versus temsirolimus (TEM) in patients (pts) with advanced clear-cell renal cell carcinoma (aCCRCC) of intermediate and poor-risk (the TemPa trial).

Sign Up to like & get
recommendations! Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.6_suppl.583

Abstract: 583Background: TEM has level 1 evidence in aRCC with poor-risk disease. No trial compared a VEGFR-TKI with TEM as first-line (1L) therapy in this disease state. Methods: We randomly assigned (1:1) treatment-naive pts with aCCRCC… read more here.

Keywords: poor risk; trial; paz; cell ... See more keywords
Photo by giamboscaro from unsplash

Aportes para pensar la cátedra de la paz desde las resistencias y proyectos de paz de los grupos étnicos en Colombia

Sign Up to like & get
recommendations! Published in 2018 at "Ratio Juris"

DOI: 10.24142/raju.v13n26a2

Abstract: The reflections that we show in this presentation come from the investigations made as part of the research projects that we presented to obtain the bachelor’s degree in basic education with emphasis in social sciences from the University… read more here.

Keywords: tedra paz; aportes para; para pensar; paz desde ... See more keywords
Photo from wikipedia

Relation between Plasma Trough Concentration of Pazopanib and Progression-Free Survival in Metastatic Soft Tissue Sarcoma Patients

Sign Up to like & get
recommendations! Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14061224

Abstract: Background: Pazopanib (PAZ) is an oral angiogenesis inhibitor approved to treat soft tissue sarcoma (STS) but associated with a large interpatient pharmacokinetic (PK) variability and narrow therapeutic index. We aimed to define the specific threshold… read more here.

Keywords: survival; progression; soft tissue; tissue sarcoma ... See more keywords