Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
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DOI: 10.3390/metabo12090852
Abstract: Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity. We have previously identified two aldehyde derivatives for pazopanib and sunitinib… read more here.
Keywords: sunitinib; pazopanib sunitinib; biological role; aldehyde derivatives ... See more keywords