Naturally occurring mutations in PB1 affect influenza A virus replication fidelity, virulence, and adaptability
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DOI: 10.1186/s12929-019-0547-4
Abstract: BackgroundMutations in the PB1 subunit of RNA-dependent RNA polymerase (RdRp) of influenza A virus can affect replication fidelity. Before the influenza A/H1N1 pandemic in 2009, most human influenza A/H1N1 viruses contained the avian-associated residue, serine,… read more here.
Keywords: human influenza; fidelity; pb1 216g; influenza ... See more keywords