Molecular pathways dysregulated by Pb2+ exposure prompts pancreatic beta-cell dysfunction.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfab121
Abstract: Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by reduced insulin sensitivity and dysfunction of β-cells. Although the increasing prevalence of diabetes worldwide is largely attributed to genetic predisposition or lifestyle factors (insufficient… read more here.
Keywords: cell; pb2 exposure; dysfunction; pathways dysregulated ... See more keywords
Chronic early-life lead exposure sensitizes adolescent rats to cocaine: Role of the dopaminergic system
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.946726
Abstract: Exposure to heavy metals has been associated with psychiatric disorders and recent studies suggest an association between childhood lead (Pb2+) intoxication and schizophrenia (SZ). In animal models, Pb2+ exposure recapitulates key neuropathological and dopaminergic system… read more here.
Keywords: dopaminergic system; pb2 exposure; pb2; exposure ... See more keywords