Risk of metachronous contralateral breast cancer in patients with primary invasive lobular breast cancer: Results from a nationwide cohort
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5235
Abstract: Lobular primary breast cancer (PBC) histology has been proposed as a risk factor for contralateral breast cancer (CBC), but results have been inconsistent. We investigated CBC risk and the impact of systemic therapy in lobular… read more here.
Keywords: breast cancer; risk; pbc; histology ... See more keywords
Expansion and intensification of humoral autoimmune response in the transition from preclinical to full‐blown primary biliary cholangitis
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29260
Abstract: We read with interest the article by Dahlqvist et al. about individuals with anti-mitochondria antibodies (AMAs) and nonestablished primary biliary cholangitis (PBC). The fortuitous finding of a positive AMA test in patients with no clinical… read more here.
Keywords: primary biliary; pbc; ama positive; humoral autoimmune ... See more keywords
Evolving role of obeticholic acid in primary biliary cholangitis
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29726
Abstract: Primary biliary cholangitis (PBC) is an immunemediated cholestatic liver disease characterized by destruction of the small intrahepatic bile ducts; if left untreated, persistent inflammation and cholestasis lead to biliary cirrhosis and end-stage liver disease. Although… read more here.
Keywords: primary biliary; pbc; receptor; biliary cholangitis ... See more keywords
Primary biliary cholangitis, DNA, and beyond: The Relative contribution of genes
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29783
Abstract: Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by immune-mediated damage to biliary epithelial cells resulting in inflammation, progressive fibrosis, cirrhosis, and liver failure. While its precise etiopathogenesis remains unclear, the disease… read more here.
Keywords: primary biliary; risk; pbc; disease ... See more keywords
Rituximab Is Ineffective for Treatment of Fatigue in Primary Biliary Cholangitis: A Phase 2 Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30099
Abstract: Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease. Half of patients experience debilitating fatigue, which is currently untreatable. Previous studies have shown muscle bioenergetic abnormalities in PBC, including increased muscle acidosis with exercise… read more here.
Keywords: rituximab; improvement; pbc; fatigue ... See more keywords
Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30145
Abstract: This American Association for the Study of Liver Diseases (AASLD) 2018 Practice Guidance on Primary Biliary Cholangitis (PBC) is an update of the PBC guidelines published in 2009. The 2018 updated guidance on PBC includes… read more here.
Keywords: pbc; american association; guidance; practice ... See more keywords
SARS‐CoV‐2 vaccination response in patients with autoimmune hepatitis and autoimmune cholestatic liver disease
Sign Up to like & getrecommendations! Published in 2022 at "United European Gastroenterology Journal"
DOI: 10.1002/ueg2.12218
Abstract: Abstract Background/Aims In this observational study, we explored the humoral and cellular immune response to SARS‐CoV‐2 vaccination in patients with autoimmune hepatitis (AIH) and patients with cholestatic autoimmune liver disease (primary sclerosing cholangitis [PSC] and… read more here.
Keywords: vaccination; psc; pbc; antibody ... See more keywords
Primär biliäre Cholangitis – etablierte und neue Therapien
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DOI: 10.1007/s00108-018-0427-0
Abstract: ZusammenfassungHintergrundPatienten mit primär biliärer Cholangitis (PBC, vormals primär biliäre Zirrhose) und unzureichendem Therapieansprechen oder Risikofaktoren haben ein deutlich erhöhtes Risiko, dass die Erkrankung bis zur Leberzirrhose und deren Komplikationen fortschreitet. Ferner ist die Lebensqualität zahlreicher… read more here.
Keywords: die; pbc; cholangitis; prim bili ... See more keywords
Autoconversion of Autoimmune Liver Diseases
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DOI: 10.1007/s10620-019-05794-1
Abstract: A 38-year-old woman with morbid obesity, gastroesophageal reflux disease, and seronegative rheumatoid arthritis that were treated with sulfasalazine and hydroxychloroquine was referred to our gastroenterology and hepatology clinic for evaluation of abnormal liver function tests… read more here.
Keywords: prednisone; pbc; treatment; gastroenterology ... See more keywords
Gender and Racial Differences in Hospitalizations for Primary Biliary Cholangitis in the USA
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DOI: 10.1007/s10620-020-06402-3
Abstract: The prevalence, characteristics, burden and trends of primary biliary cholangitis (PBC) hospitalizations in the USA remain unclear. We identified primary PBC hospitalizations from the National Inpatient Sample (NIS) 2007 through 2014 using ICD-9-CM codes. We… read more here.
Keywords: primary biliary; pbc hospitalizations; racial minorities; pbc ... See more keywords
Anti-mitochondrial Antibody-Negative Primary Biliary Cholangitis Is Part of the Same Spectrum of Classical Primary Biliary Cholangitis
Sign Up to like & getrecommendations! Published in 2021 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-021-07122-y
Abstract: Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease in which anti-mitochondrial antibodies (AMA) are the diagnostic hallmark. Whether AMA-negative PBC patients represent a different phenotype of disease is highly debated. The purpose of… read more here.
Keywords: primary biliary; pbc; ama negative; negative pbc ... See more keywords