IL‐17A produced by invariant natural killer T cells and CD3+CD56+αGalcer‐CD1d tetramer– T cells promote liver fibrosis in patients with primary biliary cholangitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2a0622-586rrrr
Abstract: Primary biliary cholangitis (PBC) is characterized as interlobular bile duct injury and fibrosis, which results from the loss of tolerance to self‐antigens. However, the exact pathologic mechanism leading to injury and fibrosis in PBC patients… read more here.
Keywords: cd56 galcer; primary biliary; pbc patients; biliary cholangitis ... See more keywords
Value of posttransplant protocol biopsies in 2 biliary autoimmune liver diseases
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DOI: 10.1097/md.0000000000028509
Abstract: Abstract The value of protocol liver graft biopsies with good liver function was evaluated in patients with primary sclerosing cholangitis (PSC) or primary biliary cholangitis (PBC). A total of 250 protocol liver biopsy reports from… read more here.
Keywords: protocol biopsies; immunosuppression therapy; pbc patients; value ... See more keywords
Platelet activation and hypercoagulability in patients with early primary biliary cholangitis compared with healthy controls
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Gastroenterology"
DOI: 10.20524/aog.2021.0572
Abstract: Background Patients with primary biliary cholangitis (PBC) who have advanced disease are hypercoagulable, with no thrombophilic factors compared to non-cholestatic cirrhotics. We investigated whether hypercoagulability is present in early-stage PBC. Methods PBC patients with biopsy-documented… read more here.
Keywords: primary biliary; healthy controls; pbc patients; hypercoagulability ... See more keywords
Gut microbial profile of treatment-naive patients with primary biliary cholangitis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1126117
Abstract: Background and aims The pathogenesis of primary biliary cholangitis (PBC) is associated with alterations of gut microbiota. We compared the gut microbiota of PBC patients and healthy controls from Zhejiang Province and assessed the use… read more here.
Keywords: treatment naive; gut microbiota; primary biliary; pbc patients ... See more keywords