S093: pneumatic balloon dilation for palliation of recurrent symptoms of achalasia after esophagomyotomy
Sign Up to like & getrecommendations! Published in 2018 at "Surgical Endoscopy"
DOI: 10.1007/s00464-018-6271-4
Abstract: BackgroundAchalasia is a chronic disease affecting the myenteric plexus of the esophagus and lower esophageal sphincter. Treatment is aimed at palliating symptoms to improve quality of life. Treatment options for symptom relapse after esophagomyotomy include… read more here.
Keywords: symptoms achalasia; dilation; recurrent; achalasia esophagomyotomy ... See more keywords
Aberrant Resting-State Functional Connectivity in the Default Mode Network in Pediatric Bipolar Disorder Patients with and without Psychotic Symptoms
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0315-6
Abstract: Mood disorders/psychosis have been associated with dysfunctions in the default mode network (DMN). However, the relative contributions of DMN regions to state and trait disturbances in pediatric bipolar disorder (PBD) remain unclear. The aim of… read more here.
Keywords: state; pediatric bipolar; default mode; connectivity ... See more keywords
Rhizosphere microbiota compositional changes reflect potato blackleg disease
Sign Up to like & getrecommendations! Published in 2019 at "Applied Soil Ecology"
DOI: 10.1016/j.apsoil.2019.03.024
Abstract: Abstract Potato blackleg disease (PBD) is one of the most serious potato bacterial diseases. Although the importance of the rhizosphere microbiota for plant growth and health is widely acknowledged, the relationship between the composition of… read more here.
Keywords: blackleg disease; pbd; potato; rhizosphere microbiota ... See more keywords
Fast and efficient zirconia‐based reversed phase chromatography for selective determination of triptans in rat plasma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.05.047
Abstract: &NA; Selective and fast chromatographic method was essential for the determination of triptans, selective serotonin receptor (5‐HT1) agonists, in biological specimens. However, selective chromatographic separation of these highly basic drugs is a challenging problem on… read more here.
Keywords: zirconia based; method; determination triptans; zirconia ... See more keywords
11. Transcathether implantation without preballoon dilation – How can echocardiography help
Sign Up to like & getrecommendations! Published in 2017 at "Journal of The Saudi Heart Association"
DOI: 10.1016/j.jsha.2017.06.023
Abstract: Abstract Type Clinical Research. Presentation Type Oral Presentation. Introduction Transcatheter aortic valve implantation (TAVI) is performed usually with preballoon dilation (PBD) which has its pros and cons. The aim of this study was to show… read more here.
Keywords: aortic valve; dilation; group; implantation ... See more keywords
Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01359
Abstract: The polo-box domain (PBD) of Plk1 is a promising target for cancer therapeutics. We designed and synthesized novel phosphorylated macrocyclic peptidomimetics targeting PBD based on acyclic phosphopeptide PMQSpTPL. The inhibitory activities of 16e on Plk1-PBD… read more here.
Keywords: plk1; box domain; pbd; plk1 pbd ... See more keywords
Inhibitors of the PLK1 polo-box domain: drug design strategies and therapeutic opportunities in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2023.2159942
Abstract: ABSTRACT Introduction Polo Like Kinase 1 (PLK1) is a key regulator of mitosis and its overexpression is frequently observed in a wide variety of human cancers, while often being associated with poor survival rates. Therefore,… read more here.
Keywords: pbd; polo box; inhibitors plk1; plk1 polo ... See more keywords
Promoting Environmental Behaviors: Applying the Health Belief Model to Diet Change
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DOI: 10.1080/17524032.2019.1702569
Abstract: ABSTRACT Very few Americans follow a plant-based diet (PBD), despite its environmental and personal benefits. To better understand motivations and intentions to adopt a PBD, this online survey study sampled 514 participants across the US,… read more here.
Keywords: model; belief model; health; pbd ... See more keywords
Pre-operative biliary drainage is associated with shortened survival time in patients with cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology Report"
DOI: 10.1093/gastro/goy049
Abstract: Abstract Background and objective Although pre-operative biliary drainage (PBD) is frequently performed in patients with cholangiocarcinoma (CCA), its impact on patient survival is unclear. Our aim was to evaluate the impact of PBD on overall… read more here.
Keywords: operative biliary; pre operative; drainage; patients cholangiocarcinoma ... See more keywords
2 A history of the ‘paediatric bipolar disorder’ epidemic: driving forces, iatrogenic consequences and lessons for psychiatric nosology
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Evidence-Based Medicine"
DOI: 10.1136/bmjebm-2019-pod.16
Abstract: Background ‘Paediatric bipolar disorder’ (PBD) is a controversial diagnosis that began in the mid-1990s when several US child psychiatric researchers hypothesised that atypical mania commonly occurred among prepubertal children in the form of chronic irritability… read more here.
Keywords: nosology; pbd; psychiatric nosology; bipolar disorder ... See more keywords
Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-20-0351
Abstract: Resistance to antibody–drug conjugates (ADCs) has been observed in both preclinical models and clinical studies. However, mechanisms of resistance to pyrrolobenzodiazepine (PBD)-conjugated ADCs have not been well characterized and thus, this study was designed to… read more here.
Keywords: pbd; resistance pyrrolobenzodiazepine; pbd conjugated; conjugated adcs ... See more keywords