Articles with "pbmc" as a keyword



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Dietary curcumin supplementation does not alter peripheral blood mononuclear cell responses to exertional heat stress

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Published in 2018 at "European Journal of Applied Physiology"

DOI: 10.1007/s00421-018-3998-5

Abstract: IntroductionCurcumin reduces gut barrier damage and plasma cytokine responses to exertional heat stress. However, the role of peripheral blood mononuclear cell (PBMC) in this response remains unclear.PurposeThis work investigated the effect of 3 days of 500 mg/day… read more here.

Keywords: responses exertional; blood; heat; exertional heat ... See more keywords
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The Activation Marker CD137 (4-1BB) Identifies a Highly Active Subset of Donor Lymphocytes Against Acute Myeloid Leukemia

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Published in 2019 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2018.12.677

Abstract: Background Donor lymphocyte infusion is an effective treatment for AML relapse post-transplant, but it has the risk of inducing graft versus host disease (GVHD). Isolating and expanding a subset of lymphocytes that contains antigen-specific T… read more here.

Keywords: activation; cd137; pbmc; unselected cells ... See more keywords
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Conjugated polymer nanoparticles based on carbazole for detecting ferric ion (III) with a large Stokes shift and high sensitivity and the application in cell imaging

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Published in 2019 at "Dyes and Pigments"

DOI: 10.1016/j.dyepig.2019.04.030

Abstract: Abstract The deficiency and excess of Fe3+ will lead to biological disorders and even many diseases. So, measuring the levels of Fe3+ in human body has drawn great attentions for health monitoring. Fluorescence method has… read more here.

Keywords: pbmc; conjugated polymer; polymer nanoparticles; cpns pbmc ... See more keywords
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Metformin alters peripheral blood mononuclear cells (PBMC) senescence biomarkers gene expression in type 2 diabetic patients.

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Published in 2020 at "Journal of diabetes and its complications"

DOI: 10.1016/j.jdiacomp.2020.107758

Abstract: BACKGROUND Although there is increasing evidence showing that cell senescence is increased in circulating PBMC in type 2 diabetes mellitus (T2DM), the data are contradictory. This study examined several senescence biomarkers, including LMNA/C transcript variants,… read more here.

Keywords: t2dm; senescence; expression; senescence biomarkers ... See more keywords
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Interactions of human mesenchymal stromal cells with peripheral blood mononuclear cells in a Mitogenic proliferation assay.

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Published in 2021 at "Journal of immunological methods"

DOI: 10.1016/j.jim.2021.113000

Abstract: BACKGROUND Immunomodulation by mesenchymal stromal cells (MSCs) is a potentially important therapeutic modality. MSCs suppress peripheral blood mononuclear cell (PBMC) proliferation in vitro, suggesting a mechanism for suppressing inflammatory responses in vivo. This study details… read more here.

Keywords: mesenchymal stromal; stromal cells; proliferation; peripheral blood ... See more keywords
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P51 Lung epithelial cell inhibition of cytokine production by peripheral blood mononuclear cells and lung lymphocytes

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Published in 2017 at "Thorax"

DOI: 10.1136/thoraxjnl-2017-210983.193

Abstract: Introduction Type 2 cytokines such as IL-5, IL-13 and IL-4 produced by primed type 2 T cells have been shown to be important in the pathogenesis of eosinophilic airway inflammation. Factors regulating the state of activation… read more here.

Keywords: lung cells; epithelial cells; cytokine; pbmc ... See more keywords
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A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.02514

Abstract: Background: We established an in vitro co-culture model involving H3N2-infection of human nasal epithelium with peripheral blood mononuclear cells (PBMC) to investigate their cross-talk during early H3N2 infection. Methods: Nasal epithelium was differentiated from human… read more here.

Keywords: nasal epithelium; human nasal; epithelium; infection ... See more keywords
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Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.594243

Abstract: The pathological mechanisms that lead to the onset and reactivation of celiac disease (CD) remain largely unknown. While gluten free diet (GFD) improves the intestinal damage and associated clinical symptoms in majority of cases, it… read more here.

Keywords: short gluten; gluten challenge; treatment; celiac disease ... See more keywords
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Innate Immune Responses to Wildtype and Attenuated Sheeppox Virus Mediated Through RIG-1 Sensing in PBMC In-Vitro

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.666543

Abstract: Sheeppox (SPP) is a highly contagious disease of small ruminants caused by sheeppox virus (SPPV) and predominantly occurs in Asia and Africa with significant economic losses. SPPV is genetically and immunologically closely related to goatpox… read more here.

Keywords: rig; immune responses; sheeppox virus; innate immune ... See more keywords
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MMP1 and MMP11 Expression in Peripheral Blood Mononuclear Cells upon Their Interaction with Breast Cancer Cells and Fibroblasts

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22010371

Abstract: Tumor-infiltrating immune cells phenotype is associated with tumor progression. However, little is known about the phenotype of the peripheral blood mononuclear cells (PBMC) from breast cancer patients. We investigated MMP1 and MMP11 expression in PBMC… read more here.

Keywords: mmp1 mmp11; breast cancer; expression; cancer ... See more keywords
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Expression of glucocorticoid receptor shows negative correlation with human B-cell engraftment in PBMC-transplanted NOGhIL-4-Tg mice.

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Published in 2018 at "Bioscience trends"

DOI: 10.5582/bst.2018.01083

Abstract: The humanized mouse system is a promising tool for analyzing human immune responses in vivo. Recently, we developed a new humanized mouse system using the severely immunodeficient NOD/Shi-scid-IL2rγnull (NOG)-hIL-4-Tg mouse, which enabled us to evaluate… read more here.

Keywords: nog hil; mice; cell; glucocorticoid receptor ... See more keywords