Abstract 7281: Predicting clinical checkpoint inhibitor responses with TumorGraft3D PBMC co-culture
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-7281
Abstract: Although immunotherapy-based therapeutics such as checkpoint inhibitors (CPI) have revolutionized cancer therapy, a lot needs to be done in the field. In preclinical settings, ex vivo models still face significant challenges in translating the results… read more here.
Keywords: cancer; culture; checkpoint inhibitor; cell ... See more keywords
Epithelial-derived galectin-9 containing exosomes contribute to the immunomodulatory effects promoted by 2’-fucosyllactose and short-chain galacto- and long-chain fructo-oligosaccharides
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DOI: 10.3389/fimmu.2022.1026031
Abstract: Introduction Early life exposure to non-digestible oligosaccharides (NDO) or microbial components is known to affect immune development. NDO in combination with a TLR9 agonist mimicking bacterial triggers (CpG) promoted the secretion of galectins through unknown… read more here.
Keywords: pbmc culture; galectin secretion; epithelial derived; derived galectin ... See more keywords