Penicillin-Binding Protein Occupancy Dataset for 18 β-Lactams and 4 β-Lactamase Inhibitors in Neisseria gonorrhoeae
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00692-23
Abstract: The manuscript represents the first N. gonorrhoeae PBP-binding data set for 22 chemically different drugs in two type strains with different genetic background. We have identified three clusters of drugs according to their PBP binding… read more here.
Keywords: binding data; lactamase inhibitors; pbp; pbp binding ... See more keywords
A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery
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DOI: 10.1371/journal.pgen.1007726
Abstract: Cell elongation in rod-shaped bacteria is mediated by the Rod system, a conserved morphogenic complex that spatially controls cell wall assembly by the glycan polymerase RodA and crosslinking enzyme PBP2. Using Escherichia coli as a… read more here.
Keywords: polymerization; system; machinery; cell elongation ... See more keywords