Dynamic Profiling of Penicillin‐Binding Protein 2a (PBP2a)‐Positive Extracellular Vesicles: Implications for Early Diagnosis and Treatment Monitoring of Methicillin‐Resistant Staphylococcus Aureus Infections
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70111
Abstract: ABSTRACT Infections caused by methicillin‐resistant staphylococci (MRS), such as methicillin‐resistant Staphylococcus aureus (MRSA), pose significant challenges to public health. The early detection of MRS infections and monitoring of antibiotic resistance profiles are critical for patient… read more here.
Keywords: extracellular vesicles; pbp2a; infection; methicillin resistant ... See more keywords
Unveiling the Potential of Bergenia Phenolics: Vitexin's Role in Allosteric Modulation of PBP2a as a Strategy against MRSA Resistance.
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DOI: 10.2174/0115680266312143240805191718
Abstract: BACKGROUND For cell wall biosynthesis, drug-resistant S. aureus uses a special protein called PBP2a, even when antibiotics are present and stop its natural processes from working. To combat this, novel therapies are required to specifically… read more here.
Keywords: pbp2a; unveiling potential; mrsa; bergenia ... See more keywords
Novel Thiazolylketenyl Quinazolinones as Potential Anti-MRSA Agents and Allosteric Modulator for PBP2a
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DOI: 10.3390/molecules28104240
Abstract: Bacterial infections caused by methicillin-resistant Staphylococcus aureus have seriously threatened public health. There is an urgent need to propose an existing regimen to overcome multidrug resistance of MRSA. A unique class of novel anti-MRSA thiazolylketenyl… read more here.
Keywords: pbp2a; anti mrsa; novel thiazolylketenyl; quinazolinones potential ... See more keywords