Invasive Group A Streptococcal Penicillin Binding Protein 2× Variants Associated with Reduced Susceptibility to β-Lactam Antibiotics in the United States, 2015–2021
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DOI: 10.1128/aac.00802-22
Abstract: All known group A streptococci [GAS] are susceptible to β-lactam antibiotics. We recently identified an invasive GAS (iGAS) variant (emm43.4/PBP2x-T553K) with unusually high minimum inhibitory concentrations (MICs) for ampicillin and amoxicillin, although clinically susceptible to… read more here.
Keywords: emm43 pbp2x; 2015 2021; pbp2x; lactam antibiotics ... See more keywords
Relationship between Penicillin-Binding Proteins Alterations and β-Lactams Non-Susceptibility of Diseased Pig-Isolated Streptococcus suis
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DOI: 10.3390/antibiotics12010158
Abstract: Streptococcus suis is a zoonotic pathogen causing disease in both animals and humans, and the emergence of increasingly resistant bacteria to antimicrobial agents has become a significant challenge globally. The objective of this study was… read more here.
Keywords: penicillin; streptococcus suis; susceptibility; binding proteins ... See more keywords