Articles with "pbp2x variants" as a keyword



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Invasive Group A Streptococcal Penicillin Binding Protein 2× Variants Associated with Reduced Susceptibility to β-Lactam Antibiotics in the United States, 2015–2021

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Published in 2022 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00802-22

Abstract: All known group A streptococci [GAS] are susceptible to β-lactam antibiotics. We recently identified an invasive GAS (iGAS) variant (emm43.4/PBP2x-T553K) with unusually high minimum inhibitory concentrations (MICs) for ampicillin and amoxicillin, although clinically susceptible to… read more here.

Keywords: emm43 pbp2x; 2015 2021; pbp2x; lactam antibiotics ... See more keywords