In vitro–In vivo Relationship and Bioequivalence Prediction for Modified-Release Capsules Based on a PBPK Absorption Model
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DOI: 10.1208/s12249-019-1566-x
Abstract: A physiologically based pharmacokinetic (PBPK) absorption model was developed in GastroPlus™ based on data on intravenous, immediate-release (IR), and modified-release (MR) drug products. The predictability of the model was evaluated by comparing predicted and observed… read more here.
Keywords: pbpk absorption; model; modified release; absorption model ... See more keywords