Articles with "pbpk models" as a keyword



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A Comparative Analysis of Physiologically Based Pharmacokinetic Models for Human Immunodeficiency Virus and Tuberculosis Infections

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Published in 2022 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00274-22

Abstract: Physiologically based pharmacokinetic (PBPK) models have gained in popularity in the last decade in both drug development and regulatory science. PBPK models differ from classical pharmacokinetic models in that they include specific compartments for tissues… read more here.

Keywords: pbpk models; based pharmacokinetic; physiologically based; drug ... See more keywords
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Current Approaches and Techniques in Physiologically Based Pharmacokinetic (PBPK) Modelling of Nanomaterials

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Published in 2020 at "Nanomaterials"

DOI: 10.3390/nano10071267

Abstract: There have been efforts to develop physiologically based pharmacokinetic (PBPK) models for nanomaterials (NMs). Since NMs have quite different kinetic behaviors, the applicability of the approaches and techniques that are utilized in current PBPK models… read more here.

Keywords: based pharmacokinetic; approaches techniques; physiologically based; pharmacokinetic pbpk ... See more keywords