Regucalcin confers resistance to amyloid‐β toxicity in neuronally differentiated PC12 cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12374
Abstract: Amyloid‐β (Aβ), a primary component of amyloid plaques, has been widely associated with the pathogenesis of Alzheimer's disease. The Ca2+‐binding protein regucalcin (RGN) plays multiple roles in maintaining cell functions by regulating intracellular calcium homeostasis,… read more here.
Keywords: pc12 cells; toxicity; neuronally differentiated; regucalcin confers ... See more keywords
Analogs of imine resveratrol alleviate oxidative stress‐induced neurotoxicity in PC12 cells via activation of Nrf2
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13209
Abstract: Oxidative stress is closely associated with neurodegenerative, cardiovascular and metabolic diseases. Resveratrol and related compounds have shown great potential as antioxidants via either direct scavenging of abundant reactive oxygen species (ROS) or activation of the… read more here.
Keywords: resveratrol; pc12 cells; imine resveratrol; activation ... See more keywords
Salidroside protected against MPP+‐induced Parkinson's disease in PC12 cells by inhibiting inflammation, oxidative stress and cell apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1719
Abstract: The present study aimed to investigate the protective effects of salidroside (SAL) on 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced PC12 cell model for Parkinson's disease. PC12 cells were pretreated with SAL in different concentrations and then exposed to MPP+.… read more here.
Keywords: mpp induced; pc12 cells; apoptosis; parkinson disease ... See more keywords
Two new alkaloids from Dendrobium nobile Lindl. exhibited neuroprotective activity, and dendrobine alleviated Aβ1−42‐induced apoptosis by inhibiting CDK5 activation in PC12 cells
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22030
Abstract: Dendrobium nobile Lindl. is registered in the Chinese Pharmacopoeia as a traditional medicine. Phytochemical investigation of the ethanol extract of D. nobile Lindl. stems yielded three alkaloid compounds, including two new compounds dendroxine B (2)… read more here.
Keywords: dendrobine; pc12 cells; nobile lindl; induced apoptosis ... See more keywords
The neuroprotective effects of alpha‐lipoic acid on an experimental model of Alzheimer's disease in PC12 cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4213
Abstract: With the growth of the aging population, the prevalence of Alzheimer's disease (AD) has increased and influenced the work and daily life of AD patients, imposing a heavy burden on society and the patients' families.… read more here.
Keywords: pc12 cells; lipoic acid; alpha lipoic; disease ... See more keywords
Comparative Study of Different Acorus Species in Potentiating Neuronal Differentiation in Cultured PC12 Cells
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DOI: 10.1002/ptr.5904
Abstract: Acori Tatarinowii Rhizoma (ATR), the rhizome of Acorus tatarinowii Schott, is a common traditional Chinese medicine being used clinically for mental disorder. However, other Acorus species herbs are all having the same Chinese name ‘Chang… read more here.
Keywords: cultured pc12; neuronal differentiation; pc12 cells; acorus species ... See more keywords
Retracted: Ganoderic Acid A exerts the cytoprotection against hypoxia‐triggered impairment in PC12 cells via elevating microRNA‐153
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6556
Abstract: Ganoderic Acid A (GAA) is often applied for healing cardiovascular and cerebrovascular ailments, but the influences in cerebral ischemia injury are still hazy. The research delved into the functions of GAA in hypoxia‐triggered impairment in… read more here.
Keywords: ganoderic acid; pc12 cells; mir 153; hypoxia ... See more keywords
Comparative assessment of neurotoxicity impacts induced by alkyl tri‐n‐butyl phosphate and aromatic tricresyl phosphate in PC12 cells
Sign Up to like & getrecommendations! Published in 2020 at "Environmental Toxicology"
DOI: 10.1002/tox.22997
Abstract: Organophosphate flame retardants (OPFRs) have become a growing concern due to their potential environmental and health risk. However, limited studies have described the toxicity, particularly neurotoxicity of alkyl and aromatic OPFRs. This study investigated the… read more here.
Keywords: pc12 cells; alkyl tri; neurotoxicity; tri butyl ... See more keywords
Acrylamide, acrylic acid, or 2‐acrylamido‐2‐methyl‐1‐propanesulfonic acid induced cytotoxic in Photobacterium phosphoreum, PC12, and SK‐N‐SH cells
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23673
Abstract: In enhancing oil recovery, more and more new water‐soluble polymers are developed to replace the high toxicity and low stability acrylamide (ACR) monomer. The common replacement monomer is acrylic acid (AA) and 2‐acrylamido‐2‐methylamido‐2‐methyl‐1‐propanesulfonic acid (AMPS),… read more here.
Keywords: acid acrylamido; toxicity; acid; pc12 cells ... See more keywords
New insights into mechanism of bisphenol analogue neurotoxicity: implications of inhibition of O-GlcNAcase activity in PC12 cells
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02525-3
Abstract: Bisphenol analogues including bisphenol A and its derivatives are ubiquitous environmental contaminants and have been linked to adverse neurodevelopment effects on animals and humans. Most toxicological research focused on estrogen receptor mediated pathways and did… read more here.
Keywords: bisphenol analogues; bisphenol analogue; pc12 cells; bisphenol ... See more keywords
Neuroprotective potency of a soy whey fermented by Cordyceps militaris SN-18 against hydrogen peroxide-induced oxidative injury in PC12 cells
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nutrition"
DOI: 10.1007/s00394-021-02679-w
Abstract: Soy whey is a byproduct generated from the processing of several soybean products. Its valorization has continued to attract significant research interest in recent times due to the nutritional and bioactive potency of its chemical… read more here.
Keywords: soy whey; soy; oxidative injury; pc12 cells ... See more keywords